Results 91 to 100 of about 42,872 (270)
Intestinal spirochaetes of the genus Brachyspira share a partially conserved 26 kilobase genomic region with Enterococcus faecalis and Escherichia coli [PDF]
, 2008 Anaerobic intestinal spirochaetes of the genus Brachyspira include both pathogenic and commensal species. The two best-studied members are the pathogenic species B. hyodysenteriae (the aetiological agent of swine dysentery) and B.
Bellgard, M.I. +5 more
core +3 more sources
Intron retention generates ANKRD1 splice variants that are co-regulated with the main transcript in normal and failing myocardium [PDF]
, 2009 [Abstract] The cardiac ankyrin repeat domain 1 protein (ANKRD1, also known as CARP) has been extensively characterized with regard to its proposed functions as a cardio-enriched transcriptional co-factor and stress-inducible myofibrillar protein.
Centeno, Alberto +5 more
core +2 more sources
Differential Proteomics of Large Extracellular Vesicles in Ovarian Cancer
PROTEOMICS, EarlyView.ABSTRACT Diverse extracellular vesicles (EVs) are present in all body fluids; however, knowledge of large EVs (lEVs) remains limited. Molecular EV profiles vary depending on EV size and the physiological circulatory system, even within the same patient. In this study, we aimed to characterize the proteomic profile of IEVs in ovarian cancer patients and
Kazuhiro Suzuki +6 more
wiley +1 more source
Designed Ankyrin Repeat Proteins as Scaffolds for Multivalent Recognition [PDF]
Biomacromolecules, 2012 Ankyrin repeat (AR) proteins are composed of tandem repeats of a basic structural motif of ca. 33 amino acid residues that form a β-turn followed by two antiparallel α-helices. Multiple repeats stack together in a modular fashion to form a scaffold that is ideally suited for the presentation of multiple functional groups and/or recognition elements ...
Jessica J, Hollenbeck +4 more
openaire +2 more sources
Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Insect Science, EarlyView.Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source
Understand spiciness: mechanism of TRPV1 channel activation by capsaicin. [PDF]
, 2017 Capsaicin in chili peppers bestows the sensation of spiciness. Since the discovery of its receptor, transient receptor potential vanilloid 1 (TRPV1) ion channel, how capsaicin activates this channel has been under extensive investigation using a variety ...
Yang, Fan, Zheng, Jie
core +2 more sources
British Journal of Haematology, EarlyView.This review highlights how studies on animal red cells have enriched our understanding of the behaviour of those from humans. A comparative perspective has enhanced our knowledge of human red cell pathophysiology Summary This review emphasises how studies on animal red cells have enriched our understanding of the behaviour of those from humans.
Kathleen M. Connolly +5 more
wiley +1 more source
Global evolution and expression analysis of BTB-containing ankyrin repeat genes in plants [PDF]
Archives of Biological Sciences, 2018 The ankyrin (ANK) repeat domain and bric-a-brac, tram-track, broad complex (BTB) domains, which are the most common protein motifs in eukaryotic proteins, regulate diverse developmental and biological processes in plants.
Guan Peiyan +6 more
doaj +1 more source
Compartmentalisation in cAMP signalling: A phase separation perspective
British Journal of Pharmacology, EarlyView.Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source
Toxins, 2020 Latest advancement of omics technologies allows in-depth characterization of venom compositions. In the present work we present a proteomic study of two snake venoms of the genus Naja i.e., Naja naja (black cobra) and Naja oxiana (brown cobra) of ...
Aisha Manuwar +8 more
doaj +1 more source