Author Correction: Tiller Number1 encodes an ankyrin repeat protein that controls tillering in bread wheat. [PDF]
Dong C +19 more
europepmc +1 more source
Imperatorin Mitigates Rosacea‐Like Inflammation by Modulating the Crosstalk Between JNK1 and STAT1
IMP treatment disrupts the interaction between JNK1 and STAT1, thereby attenuating STAT1 activity. This interference subsequently diminishes the phosphorylation and nuclear translocation of STAT1, which ultimately results in a reduced production of inflammatory cytokines and chemokines.
Xiaoxue Wang, Zexin Zhu
wiley +1 more source
Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model. [PDF]
Almosailleakh M +12 more
europepmc +1 more source
Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley +1 more source
Two single-point mutations in Ankyrin Repeat one drastically change the threshold temperature of TRPV1. [PDF]
Hori S +4 more
europepmc +1 more source
Biochemical and Structural Insights into FIH-Catalysed Hydroxylation of Transient Receptor Potential Ankyrin Repeat Domains. [PDF]
Saward BG +6 more
europepmc +1 more source
Snapshots of urea-induced early structural changes and unfolding of an ankyrin repeat protein at atomic resolution. [PDF]
Medur Gurushankar MS +2 more
europepmc +1 more source
Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. [PDF]
Strubel A +11 more
europepmc +1 more source
Transport of Designed Ankyrin Repeat Proteins through reconstituted human bronchial epithelia and protection against SARS-CoV-2. [PDF]
Künzi L +8 more
europepmc +1 more source

