Nanomechanics of Ankyrin-R Repeats Probed by AFM and SMD Simulations [PDF]
, 2010 Whasil Lee +3 more
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Neuropathology and Applied Neurobiology, Volume 52, Issue 1, February 2026.The phenotype of OBSCN variants consists of exercise intolerance ranging from myalgia and cramps to rhabdomyolysis. Symptoms are mainly induced by high‐intensity sports. Molecular analysis showing a deregulation of muscle processes associated with Ca2+ regulation, extrasarcolemmal integrity and autophagy emphasised the critical role of obscurin in ...
Heidrun H. Krämer‐Best +8 more
wiley +1 more source
Evaluation of a structural polymorphism in the ankyrin repeat and kinase domain containing 1 (ANKK1) gene and the activation of executive attention networks [PDF]
, 2006 John Fossella, Adam E. Green, Jin Fan
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An activation specific anti-Mac-1 designed ankyrin repeat protein improves survival in a mouse model of acute lung injury [PDF]
, 2022 Patrick M. Siegel +8 more
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Transcriptional outputs and condensates – formation and function
New Phytologist, Volume 249, Issue 3, Page 1145-1154, February 2026.Summary The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic ...
Stephanie Hutin +4 more
wiley +1 more source
Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase [PDF]
, 2019 Katie Pollock +5 more
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TRPA5 encodes a thermosensitive ankyrin ion channel receptor in a triatomine insect
iScienceSummary: As ectotherms, insects need heat-sensitive receptors to monitor environmental temperatures and facilitate thermoregulation. We show that TRPA5, a class of ankyrin transient receptor potential (TRP) channels absent in dipteran genomes, may ...
Marjorie A. Liénard +9 more
doaj +1 more source
Neuronal Scaffold Protein ARMS Interacts with Synaptotagmin-4 C2AB through the Ankyrin Repeat Domain with an Unexpected Mode. [PDF]
Int J Mol Sci, 2023 Zhang F, Chen J, Li Y, Ye J, Wang C.
europepmc +1 more source
Ankyrin Repeat Domain 1 Protein: A Functionally Pleiotropic Protein with Cardiac Biomarker Potential [PDF]
, 2017 Samantha Shi Min Ling +4 more
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An Activation-Specific Anti-Mac-1 Designed-Ankyrin-Repeat-Protein Attenuates Colitis in Mice. [PDF]
Life (Basel), 2023 Bojti I +10 more
europepmc +1 more source