Ankyrin repeats in context with human population variation. [PDF]
PLoS Computational Biology, 2021 Ankyrin protein repeats bind to a wide range of substrates and are one of the most common protein motifs in nature. Here, we collate a high-quality alignment of 7,407 ankyrin repeats and examine for the first time, the distribution of human population ...
Javier S Utgés +4 more
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Sequence and Structure-Based Analyses of Human Ankyrin Repeats [PDF]
Molecules, 2022 Ankyrin is one of the most abundant protein repeat families found across all forms of life. It is found in a variety of multi-domain and single domain proteins in humans with diverse number of repeating units.
Broto Chakrabarty, Nita Parekh
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Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins. [PDF]
Mol Biol Cell, 2023 Willet AH, Chen JS, Ren L, Gould KL.
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Mask, the Drosophila ankyrin repeat and KH domain-containing protein, affects microtubule stability. [PDF]
J Cell Sci, 2021 Martinez D +7 more
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Elevated SH3 and Multiple Ankyrin Repeat Domains 2 Expression Correlates With Improved Glioma Prognosis. [PDF]
Int J GenomicsLi W, Shi H, He J.
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Deciphering the roles of subcellular distribution and interactions involving the MEF2 binding region, the ankyrin repeat binding motif and the catalytic site of HDAC4 in Drosophila neuronal morphogenesis [PDF]
BMC BiologyBackground Dysregulation of nucleocytoplasmic shuttling of histone deacetylase 4 (HDAC4) is associated with several neurodevelopmental and neurodegenerative disorders.
Wei Jun Tan +3 more
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The Negative Role of Ankyrin-Repeat and SOCS-Box Protein 9 in PAR1 Expression and the MAPK Signaling Pathway in Bovine Granulosa Cells. [PDF]
Biology (Basel)Naranjo Gonzalez D, Ndiaye K.
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Frontiers in Physiology, 2023 Neuronal ankyrin-B is an intracellular scaffolding protein that plays multiple roles in the axon. By contrast, relatively little is known about the function of ankyrin-B in dendrites, where ankyrin-B is also localized in mature neurons.
Julie P. Gupta +2 more
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An ankyrin repeat chaperone targets toxic oligomers during amyloidogenesis. [PDF]
Protein Sci, 2023 AbstractNumerous age‐linked diseases are rooted in protein misfolding; this has motivated the development of small molecules and therapeutic antibodies that target the aggregation of disease‐linked proteins. Here we explore another approach: molecular chaperones with engineerable protein scaffolds such as the ankyrin repeat domain (ARD).
Gupta A, Lu C, Wang F, Chou TF, Shan SO.
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