Structure, function and inhibition of poly(ADP-ribose)polymerase, member 14 (PARP14) [PDF]
Levonis, Stephan M +3 more
core +1 more source
GATA binding protein 2 mediated ankyrin repeat domain containing 26 high expression in myeloid-derived cell lines. [PDF]
Jiang YZ +13 more
europepmc +1 more source
Phase I Clinical Evaluation of Designed Ankyrin Repeat Protein [99mTc]Tc(CO)3-(HE)3-Ec1 for Visualization of EpCAM-Expressing Lung Cancer. [PDF]
Zelchan R +15 more
europepmc +1 more source
Mask, the Drosophila ankyrin repeat and KH domain-containing protein, affects microtubule stability.
Martinez D +7 more
europepmc +1 more source
ArfGAP with the SH3 Domain, Ankyrin Repeat and PH Domain 1 Inversely Regulates Programmed Death-Ligand 1 Through Negative Feedback of Phosphorylated Epithelial Growth Factor Receptor and Activation of Nuclear Factor-Kappa B in Non-Small Cell Lung Cancer. [PDF]
Chiba N +8 more
europepmc +1 more source
The Designed Ankyrin Repeat Protein Antiviral Ensovibep for Nonhospitalized Patients With Coronavirus Disease 2019: Results From EMPATHY, a Randomized, Placebo-Controlled Phase 2 Study. [PDF]
Kingsley J +22 more
europepmc +1 more source
Thermostable designed ankyrin repeat proteins (DARPins) as building blocks for innovative drugs
Schilling J +8 more
europepmc +1 more source
Preclinical evaluation of EpCAM-binding designed ankyrin repeat proteins (DARPins) as targeting moieties for bimodal near-infrared fluorescence and photoacoustic imaging of cancer. [PDF]
Houvast RD +14 more
europepmc +1 more source
A phase 1b/2 study evaluating efficacy and safety of MP0250, a designed ankyrin repeat protein (DARPin) simultaneously targeting vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF), in combination with bortezomib and dexamethasone, in patients with relapsed or refractory multiple myeloma. [PDF]
Knop S +19 more
europepmc +1 more source
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Ankyrin repeats as a dimerization module
Biochemical and Biophysical Research Communications, 2018Legionella pneumophila is a pathogen, causing severe pneumonia in humans called Legionnaires' disease. AnkC (LegA12) is a poorly characterized 495-residue effector protein conserved in multiple Legionella species. Here, we report the crystal structure of a C-terminally truncated AnkC (2-384) at 3.2 Å resolution.
Guennadi Kozlov +8 more
openaire +2 more sources

