Results 31 to 40 of about 55,065 (286)
Biomedicines, 2022 Type 2 diabetes mellitus (T2DM) is characterized by endothelial dysfunction, increased thrombogenicity, and inflammation. The soluble human F11 receptor (sF11R) and annexin A5 (ANXA5) play crucial roles in inflammatory thrombosis and atherosclerosis.
Ajibola Adedayo +15 more
doaj +1 more source
BMC Cancer, 2023 Background Annexins are a family of proteins involved in a wide variety of cellular processes such as inflammation, proliferation, differentiation, apoptosis, migration and membrane repair. However, the role of most Annexins in renal cell carcinoma (RCC)
Li-Hui Wang +3 more
doaj +1 more source
Annexins and Endocytosis [PDF]
Traffic, 2007 Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have multiple roles in membrane traffic. Historically, this has been based on the in vitro properties of annexins and their localization to specific membrane compartments. However, recent functional evidence supports a role for annexins in specific membrane traffic steps,
Clare E, Futter, Ian J, White
openaire +2 more sources
Mechanisms of Endothelial Cell Membrane Repair: Progress and Perspectives
Cells, 2023 Endothelial cells are the crucial inner lining of blood vessels, which are pivotal in vascular homeostasis and integrity. However, these cells are perpetually subjected to a myriad of mechanical, chemical, and biological stresses that can compromise ...
Duoduo Zha +5 more
doaj +1 more source
‘Annexins’ themed section [PDF]
British Journal of Pharmacology, 2015 Linked ArticlesThis article is part of a themed section on Annexins VII Programme.
R J, Flower, M, Perretti
openaire +2 more sources
Molecular analysis of the annexin gene family in soybean
Biologia Plantarum, 2013 Annexins play a crucial role in plant development and response to environmental stimuli. In this study, a total of 23 annexin genes (GmANN1 - GmANN23) were identified from the soybean genome database and for two of them (GmANN11 and GmANN14), complete ...
Y. M. Feng +6 more
doaj +1 more source
Interplay of membrane crosslinking and curvature induction by annexins
Scientific Reports, 2022 Efficient plasma membrane repair (PMR) is required to repair damage sustained in the cellular life cycle. The annexin family of proteins, involved in PMR, are activated by Ca2+ influx from extracellular media at the site of injury. Mechanistic studies of
Anna Mularski +6 more
doaj +1 more source
International Journal of Molecular Sciences, 2018 Glaucoma is one of the leading causes of irreversible visual loss, which has been estimated to affect 3.5% of those over 40 years old and projected to affect a total of 112 million people by 2040. Such a dramatic increase in affected patients demonstrates the need for continual improvement in the way we diagnose and treat this condition.
Timothy E. Yap +4 more
openaire +5 more sources
Annexin–Actin Interactions [PDF]
Traffic, 2004 The actin cytoskeleton is a malleable framework of polymerised actin monomers that may be rapidly restructured to enable diverse cellular activities such as motility, endocytosis and cytokinesis. The regulation of actin dynamics involves the coordinated activity of numerous proteins, among which members of the annexin family of Ca2+‐ and phospholipid ...
Matthew J, Hayes +3 more
openaire +2 more sources
Molecules, 2022 Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente +4 more
doaj +1 more source