Results 21 to 30 of about 7,097 (288)
Pathobiological functions and clinical implications of annexin dysregulation in human cancers
Frontiers in Cell and Developmental Biology, 2022 Annexins are an extensive superfamily of structurally related calcium- and phospholipid-binding proteins, largely conserved and widely distributed among species.
Llara Prieto-Fernández +12 more
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Biomedicines, 2022 Type 2 diabetes mellitus (T2DM) is characterized by endothelial dysfunction, increased thrombogenicity, and inflammation. The soluble human F11 receptor (sF11R) and annexin A5 (ANXA5) play crucial roles in inflammatory thrombosis and atherosclerosis.
Ajibola Adedayo +15 more
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Annexins and Endocytosis [PDF]
Traffic, 2007 Annexins are calcium‐ and phospholipid‐binding proteins that have been proposed to have multiple roles in membrane traffic. Historically, this has been based on the in vitro properties of annexins and their localization to specific membrane compartments. However, recent functional evidence supports a role for annexins in specific membrane traffic steps,
Clare E, Futter, Ian J, White
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Functional Association between Regulatory RNAs and the Annexins [PDF]
, 2018 Cells respond to pathophysiological states by activation of stress-induced signalling. Regulatory non-coding microRNAs (miRNAs) often form stable feed-forward loops which ensure prolongation of the signal, contributing to sustained activation. Members of
Katia Monastyrskaya +1 more
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BMC Cancer, 2023 Background Annexins are a family of proteins involved in a wide variety of cellular processes such as inflammation, proliferation, differentiation, apoptosis, migration and membrane repair. However, the role of most Annexins in renal cell carcinoma (RCC)
Li-Hui Wang +3 more
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Mechanisms of Endothelial Cell Membrane Repair: Progress and Perspectives
Cells, 2023 Endothelial cells are the crucial inner lining of blood vessels, which are pivotal in vascular homeostasis and integrity. However, these cells are perpetually subjected to a myriad of mechanical, chemical, and biological stresses that can compromise ...
Duoduo Zha +5 more
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Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization [PDF]
, 2009 Initiation of mineralization during endochondral ossification is a multistep process and has been assumed to correlate with specific interactions of annexins A5 and A6 and collagens.
Pausch, F +11 more
core +1 more source
Molecular analysis of the annexin gene family in soybean
Biologia Plantarum, 2013 Annexins play a crucial role in plant development and response to environmental stimuli. In this study, a total of 23 annexin genes (GmANN1 - GmANN23) were identified from the soybean genome database and for two of them (GmANN11 and GmANN14), complete ...
Y. M. Feng +6 more
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Glycosylation of annexin I and annexin II
Biochemical and Biophysical Research Communications, 1992 Human placental annexin I and annexin II were shown to be glycosylated by one-dimensional affinity blotting with the lectin concanavalin A, which recognizes D-mannose and D-glucose residues. Further evidence that annexin I and annexin II are glycosylated was provided by the finding that these proteins incorporated D-[2,6-3H]mannose and D-[6-3H]glucose ...
F, Goulet, K G, Moore, A C, Sartorelli
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Annexins and cardiovascular diseases: Beyond membrane trafficking and repair
Frontiers in Cell and Developmental Biology, 2022 Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide. The main cause underlying CVD is associated with the pathological remodeling of the vascular wall, involving several cell types, including endothelial cells, vascular smooth ...
Nerea Méndez-Barbero +10 more
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