Results 31 to 40 of about 5,734 (257)
Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
Nature Communications, 2017 The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are ...
Theresa Louise Boye +7 more
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Trends in Cell Biology, 1997 Ten years after the discovery of annexins, we are just understanding the functions of these enigmatic proteins, been a frustrating decade for those in this field because appear capable of performing a multitude of function: to the sceptic apparently do nothing in vivo.
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OsANN4 modulates ROS production and mediates Ca2+ influx in response to ABA
BMC Plant Biology, 2021 Background Plant annexins are calcium- and lipid-binding proteins that have multiple functions, and a significant amount of research on plant annexins has been reported in recent years.
Qian Zhang +8 more
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Analysis of the Expression and Prognostic Value of Annexin Family Proteins in Bladder Cancer
Frontiers in Genetics, 2021 BackgroundBladder cancer (BC) is the most common tumor of the urinary system. Non-muscle-invasive bladder cancer (NMIBC) has a high recurrence rate after surgery, and patients with muscle-invasive bladder cancer (MIBC) have poor quality of life after ...
WenBo Wu +4 more
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Lectins with Potential for Anti-Cancer Therapy
Molecules, 2015 This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins,
Tammy Yau +3 more
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Special Issue “Recent Developments in Annexin Biology”
Cells, 2020 Discovered over 40 years ago, the annexin proteins were found to be a structurally conserved subgroup of Ca2+-binding proteins. While the initial research on annexins focused on their signature feature of Ca2+-dependent binding to membranes, over the ...
Ursula Rescher +3 more
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Frontiers in Plant Science, 2021 Annexins are a multifunctional class of calcium-binding proteins in plants, and their physiological functions and regulation in response to drought stress remain to be elucidated. Here, we found that AtANN2 and AtANN3 conferred to drought tolerance under
Ting Liu +9 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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Cells, 2020 The plasma membrane surrounds every single cell and essentially shapes cell life by separating the interior from the external environment. Thus, maintenance of cell membrane integrity is essential to prevent death caused by disruption of the plasma ...
Poul Martin Bendix +16 more
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Genome-wide comparative analysis of annexin superfamily in plants. [PDF]
PLoS ONE, 2012 Most annexins are calcium-dependent, phospholipid-binding proteins with suggested functions in response to environmental stresses and signaling during plant growth and development. They have previously been identified and characterized in Arabidopsis and
Sravan Kumar Jami +4 more
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