Results 11 to 20 of about 7,097 (288)
Bioinformatics analysis of bacterial annexins--putative ancestral relatives of eukaryotic annexins. [PDF]
Annexins are Ca(2+)-binding, membrane-interacting proteins, widespread among eukaryotes, consisting usually of four structurally similar repeated domains. It is accepted that vertebrate annexins derive from a double genome duplication event.
Praveen Kumar Kodavali +3 more
doaj +2 more sources
Annexins as disease modifiers. [PDF]
The annexins are a family of calcium-dependent phospholipid binding proteins which are present in all eukaryotes. There are currently 12 identified human annexins all of which contain unique calcium binding sites, encoded in the highly conserved annexin repeat motifs within the C terminal core.
Fatimathas, Lux, Moss, Stephen E.
openaire +4 more sources
Interplay of membrane crosslinking and curvature induction by annexins [PDF]
Efficient plasma membrane repair (PMR) is required to repair damage sustained in the cellular life cycle. The annexin family of proteins, involved in PMR, are activated by Ca2+ influx from extracellular media at the site of injury. Mechanistic studies of
Anna Mularski +6 more
doaj +2 more sources
Annexins have long been though to be involved in exocytosis, possibly by helping to create close interactions between membranes destined to undergo fusion. In this article, we examine recent observations that implicate annexins in three different steps of the endocytic pathway, suggesting that annexins may be universal modulators of membrane ...
Gruenberg, Jean, Emans, Neil
openaire +4 more sources
Plant annexins are a multigene family of phospholipid-binding, calcium-dependent proteins that respond to signals and environmental challenges as plants grow and develop.
Mohammad Faizan +8 more
doaj +2 more sources
Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics [PDF]
Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic phospholipids in cellular membranes at elevated Ca2+ levels.
Volker Gerke +6 more
doaj +2 more sources
SummaryAnnexins are multifunctional lipid‐binding proteins. Plant annexins are expressed throughout the life cycle and are under environmental control. Their association or insertion into membranes may be governed by a range of local conditions (Ca2+, pH, voltage or lipid identity) and nonclassical sorting motifs.
Anuphon, Laohavisit, Julia M, Davies
openaire +2 more sources
RNA-binding is an ancient trait of the Annexin family
Introduction: The regulation of intracellular functions in mammalian cells involves close coordination of cellular processes. During recent years it has become evident that the sorting, trafficking and distribution of transport vesicles and mRNA granules/
Sudarshan S. Patil +7 more
doaj +1 more source
Annexins as Ca2+/phospholipid-binding proteins are involved in the control of many biological processes essential for plant growth and development. In a previous study, we had shown, using a proteomic approach, that the synthesis of two annexins is ...
O. A. Pavlova +4 more
doaj +1 more source
Molecular analysis of Annexin expression in cancer
Background Uptake of apoptotic cells induces a tolerogenic phenotype in phagocytes and promotes peripheral tolerance. The highly conserved Annexin core domain, present in all members of the Annexin family, becomes exposed on the apoptotic cell-surface ...
Tobias Hein +2 more
doaj +1 more source

