Results 51 to 60 of about 626,524 (297)
Vibration Analysis of FGM Annular Plate with Linearly Varying Thickness for Several Boundary Conditions [PDF]
Mechanics of Advanced Composite StructuresThe present article depicts the influence of linear thickness variation on the free axisymmetric vibration of functionally graded material annular plates. For this, three different types of boundary conditions have been taken into consideration.
Sumit Kumar Sharma, Neha Ahlawat
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Vibration Properties of an Annular Sector Plate [PDF]
, 1989 Free vibration of an annular sector plate simply supported along the radial edges is examined. Natural frequencies of the annular sector plate with different boundary conditions along the circular edges are obtained for wide ranges of the aspect ratio ...
平川, 倫明 +3 more
core
Advances in Materials Science and Engineering, 2014 A three-dimensional elasticity theory by means of a state-space based differential quadrature method is presented for free vibration analysis of fiber metal laminate annular plate.
G. H. Rahimi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Annular Supersonic Ejector Design and Optimization [PDF]
, 2012 An ejector is a device that entrains a secondary flow into a high speed stream that is generated by expansion of high pressure motive gas [1]. These ejectors can be broadly classified into central ejectors and annular ejectors.
Venkat S. Iyengar +5 more
core +1 more source
The total sound power of some forced vibrations of a clamped annular plate in fluid
Archives of Acoustics, 2002 The energetic aspect of sound radiation by a~clamped annular plate has been considered. The total sound power, active and reactive, was computed using the impedance approach, which makes possible to correctly design some acoustic systems ...
W. P. Rdzanek
doaj