Results 71 to 80 of about 626,524 (297)

A refined higher-order shear deformation theory for bending, vibration and buckling analysis of functionally graded sandwich plates [PDF]

, 2015
A refined higher-order shear deformation theory for bending, vibration and buckling analysis of functionally graded sandwich plates is presented in this paper.
Thai, Huu-Tai, Vo, Thuc, Nguyen, Kien
core   +1 more source

Enhanced fracture fixation stability and osseointegration through over-compression: Design of an annular compression plate for posterolateral tibial plateau fractures

Materials & Design
Posterolateral tibial plateau fractures (PTPF) fixation is challenged by fragment instability and insufficient biomechanical consideration, leading to joint surface incongruity and impaired fracture healing.
Chao-Wei Huang, Xin-Cheng Dai, Yu-Tzu Wang   +2 more
doaj   +1 more source

Stability of a composite thick plate with an inhomogeneous field of initial stresses

MATEC Web of Conferences, 2018
We discuss the linear stability analysis for a rectangular twolayered elastic plate. Each layer of the plate was obtained due to inflation of an annular wedge of a cylinder. As a result, in the plate there are initial stresses.
Eremeev Vadim V., Shubchinskaya Natalia Y., Ivashchenko Denis V., Minko Vsevolod A.   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Influence of Parameters of Core Bingham Material on Critical Behaviour of Three-Layered Annular Plate

Studia Geotechnica et Mechanica, 2017
The paper presents the dynamic response of annular three-layered plate subjected to loads variable in time. The plate is loaded in the plane of outer layers. The plate core has the electrorheological properties expressed by the Bingham body model.
Pawlus Dorota
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Temperature Effect on Stability of Clamped-Clamped Composite Annular Plate with Damages. [PDF]

Materials (Basel), 2021
Pawlus D.
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source