Results 121 to 130 of about 29,991,250 (177)

The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels

, 2011
The Ca(2+)-activated Cl(-) channels (CaCCs) are involved in a variety of physiological functions, such as transepithelial anion transport, smooth muscle contraction and olfaction.
Ferrera L., Paolo Scudieri, Loretta Ferrera, Sondo E., Scudieri, Paolo, Ferrera, Loretta, Luis J. V. Galietta, Galietta, Luis J. V., Scudieri P., Galietta L. J. V., Elvira Sondo, Sondo, Elvira   +11 more
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High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma

Scientific Reports
Human papilloma virus-negative head and neck squamous cell carcinoma (HNSCC) frequently harbors 11q13 amplifications. Among the oncogenes at this locus, CCND1 and ANO1 are linked to poor prognosis; however, their individual roles in treatment resistance ...
Solenne Bourdier, Anne-Sophie Fisch, Keziban Merve Alp, Ridhima Das, Philipp Mertins, Ingeborg Tinhofer   +5 more
doaj   +1 more source

초기 신경발생과정에 관여하는 anoctamin chloride 채널의 역할 [PDF]

, 2012
학위논문 (석사)-- 서울대학교 융합과학기술대학원 : 분자의학 및 바이오제약학과, 2012. 8. 오우택.The embryonic neurogenesis which new neurons are generated in the embryonic brain is critical for the development of the central nervous system.
오정은
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Rhabdomyolysis as an uncommon manifestation of anoctamin-5 muscular dystrophy [PDF]

Background: Anoctamin-5 (ANO5) muscular dystrophy is a rare neuromuscular disease. Muscular weakness and impaired gait may be evident at the moment of diagnosis, serving as defining characteristics of additional muscular dystrophies.
Marta Rodrigues, Tiago Dias da Costa, António Mateus-Pinheiro, Sónia Moreira   +3 more
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Highlights for the 6th International Ion Channel Conference: ion channel structure, function, disease and therapeutics

Acta Pharmaceutica Sinica B, 2017
To foster communication and interactions amongst international scholars and scientists in the field of ion channel research, the 6th International Ion Channel Conference (IICC-2017) was held between June 23–27, 2017 in the eastern coastal city of Qingdao,
Limei Wang, Kewei Wang
doaj   +1 more source

Anoctamin 1 antagonism potentiates conventional tocolytic-mediated relaxation of pregnant human uterine smooth muscle. [PDF]

J Physiol Sci, 2021
Hyuga S, Parry RC, Danielsson J, Vink J, Fu XW, Wu A, Dan W, Yim PD, Gallos G.   +8 more
europepmc   +1 more source

ER stress-induced ITPR1/ANO1 signaling drives trigeminal neuropathic pain through calcium-dependent neuronal hyperexcitability

The Journal of Headache and Pain
Background Endoplasmic reticulum (ER) stress has been implicated in various chronic pain conditions, but its role in trigeminal neuropathic pain (TNP) remains unclear.
Huan-Jun Lu, Jia-Wen Shen, Ning-Yi Ren, Nan Hu, Jian-Ke Cen, Meng-Xuan Huang, Si-Yuan Song, Ling-Jie Ma, Xiao-Bo Wu, Xia Li, Mei-Xian Li, Hao Wu, Gyu-Sang Hong, Uhtaek Oh, Yong-Jing Gao   +14 more
doaj   +1 more source

Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential

Frontiers in Pharmacology
Background: Prostate cancer and non-small cell lung cancer (NSCLC) present significant challenges in the development of effective therapeutic strategies.
Yohan Seo, Sion Lee, Minuk Kim, Dongguk Kim, Sung Baek Jeong, Raju Das, Armin Sultana, SeonJu Park, Nguyen Xuan Nhiem, Phan Thi Thanh Huong, Oh-Bin Kwon, Wan Namkung, Joohan Woo, Joohan Woo   +13 more
doaj   +1 more source

Bioinformatic Characterization of the Anoctamin Family of Calcium-Activated Chloride Channels and the Establishment of Homology Using Protein Sequence Analysis [PDF]

, 2015
The Anoctamin Family of proteins is closely related to both Transmembrane Channel-like proteins and DUF221 proteins who's functions are largely unknown. These three families are grouped into a larger superfamily called the Anoctamin Superfamily. Here, we
McLaughlin, Daniel
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Anoctamin-1 [PDF]

, 2020
openaire   +1 more source