Results 91 to 100 of about 2,952 (151)

Molecular Mimicry Between Epstein‐Barr Virus and Human Herpesvirus‐6 Proteins and Central Nervous System Proteins: Implications for T and B Cell Immunogenicity in an In Silico Study

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background The Epstein‐Barr virus (EBV) and human herpesvirus 6 (HHV‐6) are frequently linked to neuropsychiatric illnesses such as multiple sclerosis, depression, and chronic fatigue syndrome/myalgic encephalomyelitis. These viruses may induce autoimmune reactions by molecular mimicry, leading to damage to self‐epitopes in the central nervous
Abbas F. Almulla, Muslimbek G. Normatov, Thitiporn Supasitthumrong, Michael Maes   +3 more
wiley   +1 more source

Triterpenoid glycosides from the rhizomes of Allium ascalonicum and their anoctamin-1 inhibitory activity

Natural Product Research, 2020
Ten triterpenoid glycosides including two undescribed compounds (1 and 2) were isolated from the methanol extract of Allium ascalonicum rhizomes. These compounds were structurally elucidated to be 3β-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-19α-hydroxyolean-12-ene-28-oic acid 28-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl] ester (1), 3-O-β ...
Nguyễn Thị, Dương Thị Dung, Trần Thúy Nga, Vu Thi Xuan, Vũ Văn Đoán, Bùi Hữu Tài, Nguyễn Xuân Nhiệm, Phạm Hải Yến, Phan Văn Kiệm, Yohan Seo, W. Namkung, SeonJu Park, Seung Hyun Kim   +12 more
openaire   +2 more sources

Characterization of TMEM16F-Specific Affibodies and Their Cellular Effects

Membranes
The TMEM16 (Anoctamin) family comprises a group of transmembrane proteins involved in diverse physiological processes, including ion transport and phospholipid scrambling.
Eunyoung Kim, Jinho Bang, Sunghyun Kim, Byoung-Cheol Lee   +3 more
doaj   +1 more source

How Epstein–Barr Virus Drives Multiple Sclerosis: New Mechanisms and Therapeutic Lessons

MedComm, Volume 7, Issue 7, July 2026.
Dan Liu, Wenhui Fan, Pengtao Jiao
wiley   +1 more source

Differential expression of anoctamin 1 in human epithelial ovarian cancer.

, 2021
Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published and public microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of ...
openaire   +2 more sources

Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux

Cellular Physiology and Biochemistry, 2014
Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco, Cristina Cosentino, Laura Sirna, Roberta Romano, Silvia Cursano, Alessandra Mongia, Giampaolo Pompeo, Julie di Bernardo, Claudio Ceccarelli, Giovanni Tallini, Kerry J. Rhoden   +10 more
doaj   +1 more source

Control of Lung Myofibroblast Activation by Anoctamine-1 [PDF]

C57. EXTRACELLULAR MATRIX AND SUBCELLULAR DYNAMICS IN COMPLEX LUNG DISEASE, 2020
N.O. Dulin, E.B. Reed, P.S. Woods, G.M. Mutlu   +3 more
openaire   +1 more source

Control of Ion Transport by Tmem16a Expressed in Murine Intestine

Frontiers in Physiology, 2019
Cl– secretion by the human and murine intestinal epithelium occurs through the cystic fibrosis transmembrane conductance regulator (cftr). However, the Ca2+ activated Cl– channel Tmem16a was shown to contribute to Cl– secretion, mainly, but not ...
Karl Kunzelmann, Raquel Centeio, Podchanart Wanitchakool, Inês Cabrita, Roberta Benedetto, Tultul Saha, Kazi Mirajul Hoque, Kazi Mirajul Hoque, Rainer Schreiber   +8 more
doaj   +1 more source

High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma

Scientific Reports
Human papilloma virus-negative head and neck squamous cell carcinoma (HNSCC) frequently harbors 11q13 amplifications. Among the oncogenes at this locus, CCND1 and ANO1 are linked to poor prognosis; however, their individual roles in treatment resistance ...
Solenne Bourdier, Anne-Sophie Fisch, Keziban Merve Alp, Ridhima Das, Philipp Mertins, Ingeborg Tinhofer   +5 more
doaj   +1 more source

Highlights for the 6th International Ion Channel Conference: ion channel structure, function, disease and therapeutics

Acta Pharmaceutica Sinica B, 2017
To foster communication and interactions amongst international scholars and scientists in the field of ion channel research, the 6th International Ion Channel Conference (IICC-2017) was held between June 23–27, 2017 in the eastern coastal city of Qingdao,
Limei Wang, Kewei Wang
doaj   +1 more source