Results 161 to 170 of about 29,694,765 (175)

Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells

Biological Chemistry, 2011
Two families of proteins, the bestrophins (Best) and the recently cloned TMEM16 proteins (anoctamin, Ano), recapitulate properties of Ca2+-activated Cl- currents.
Karl Kunzelmann, Krongkarn Chootip, Joana Raquel Martins   +2 more
exaly   +2 more sources

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Calcium-regulated chloride channel anoctamin-1 is present in the suprachiasmatic nuclei of rats

NeuroReport, 2018
Calcium-regulated chloride channel (CaCC) anoctamin-1 has been recently identified in neurons. In neurons, which express the Na-K-2Cl cotransporter, activation of CaCCs increases firing frequency, by reversion between the Cl equilibrium potential and the membrane resting potential, leading to membrane depolarization by Cl extrusion from the cell ...
Raúl, Aguilar-Roblero, Adriana, Mejía-López, Dominique, Cortés-Pedroza, José L, Chavez-Juárez, Miguel A, Gutierrez-Monreal, Gabriela, Domínguez, Paula, Vergara, José, Segovia   +7 more
openaire   +2 more sources

A mathematical model of the effects of anoctamin-1 loss on intestinal slow wave entrainment

2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2017
The interstitial cells of Cajal (ICC) generate electrophysiological events called slow waves that regulate the motility of the gastrointestinal (GI) tract. Recent studies have demonstrated that the Ca2+-activated Cl- -channel, encoded by the anoctamin1 (Ano1) protein, has a major role in regulating intestinal slow waves and motility.
Anna Qian, Shawn Means, Leo K. Cheng, James Sneyd, Peng Du 0012   +4 more
openaire   +3 more sources

Use of anoctamin 1 (ANO1) to evaluate interstitial cells of Cajal in Hirschsprung’s disease

Pediatric Surgery International, 2015
Interstitial cells of Cajal (ICCs) are pacemaker cells involved in facilitating neurotransmission and the generation of slow electrical waves necessary for colonic peristalsis. Their distribution has been found to be abnormal in the aganglionic and ganglionic colon in Hirschsprung's disease (HSCR) using c-kit-labelling.
David, Coyle, Danielle A M, Kelly, Anne Marie, O'Donnell, John, Gillick, Prem, Puri   +4 more
openaire   +2 more sources

Expression patterns of anoctamin 1 and anoctamin 2 chloride channels in the mammalian nose

Cell and Tissue Research, 2012
Calcium-activated chloride channels are expressed in chemosensory neurons of the nose and contribute to secretory processes and sensory signal transduction. These channels are thought to be members of the family of anoctamins (alternative name: TMEM16 proteins), which are opened by micromolar concentrations of intracellular Ca(2+).
Kristin, Dauner, Judith, Lissmann, Semir, Jeridi, Stephan, Frings, Frank, Möhrlen   +4 more
openaire   +2 more sources

Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract

Pflugers Archiv European Journal of Physiology, 2023
Karl Kunzelmann, Rainer Schreiber, Jiraporn Ousingsawat   +2 more
exaly  

Dilated cardiomyopathy in patients with mutations in anoctamin 5

International Journal of Cardiology, 2013
Karim Wahbi, Tanya Stojković, A Behin   +2 more
exaly  

Homodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors

Pflugers Archiv European Journal of Physiology, 2015
Fritz Markwardt, Günther Schmalzing, Silvia Detro-Dassen   +2 more
exaly  

TMEM16F/Anoctamin 6 in Ferroptotic Cell Death

Cancers, 2019
Karl Kunzelmann, Rainer Schreiber
exaly  

Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk

Proceedings of the National Academy of Sciences of the United States of America, 2019
Ingemar Ernberg, Karin Lundberg, Julia Butt   +2 more
exaly