Results 81 to 90 of about 29,991,200 (150)
Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicing [PDF]
, 2011 Background TMEM16A (Anoctamin 1; ANO1) is an eight transmembrane protein that functions as a calcium-activated chloride channel. TMEM16A in human exhibits alternatively spliced exons (6b, 13 and 15), which confer important roles in the ...
Fiona C Britton +2 more
core +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: Calcium-activated chloride channels (CaCCs) regulate numerous physiological processes including cell proliferation, migration, and extracellular matrix secretion. T16Ainh-A01 and CaCCinh-A01 are selective inhibitors of CaCCs.
Xiang-qin Tian +5 more
doaj +1 more source
Molecular Mechanisms of Electric Signals Generated at Corneal Wounds
The FASEB Journal, Volume 40, Issue 16, 31 August 2026.Corneal injury triggers cell signaling (including calcium waves) leading to ion channel up‐regulation, increased ion pumping, and enhanced wound electric signals which stimulate wound healing. ABSTRACT Over 150 years ago, it was demonstrated that wounds produce electric fields and currents.
Brian Reid, Guillaume Luxardi, Min Zhao
wiley +1 more source
, 2020 Ten triterpenoid glycosides including two undescribed compounds (1 and 2) were isolated from the methanol extract of Allium ascalonicum rhizomes. These compounds were structurally elucidated to be 3β-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-19α ...
Vu Thi Xuan (8343294) +12 more
core +1 more source
The Journal of Physiology, Volume 604, Issue 15, Page 6348-6368, 1 August 2026.Abstract figure legend Physiological functions of PKD1, a large transmembrane polycystin protein, are unclear. Previous results obtained using germline non‐specific knockout mice suggested that PKD1 regulates arterial smooth muscle cell contractility.
Angélica K. Bernardelli +7 more
wiley +1 more source
European Journal of Pain, Volume 30, Issue 6, July 2026.ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian +8 more
wiley +1 more source
Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics
Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu +3 more
wiley +1 more source
Anoctamin 2/TMEM16B: A calcium-activated chloride channel in olfactory transduction [PDF]
, 2012 In vertebrate olfactory transduction, a Ca2+-dependent Cl- efflux greatly amplifies the odorant response. The binding of odorants to receptors in the cilia of olfactory sensory neurons activates a transduction cascade that involves the opening of cyclic ...
Pifferi S., Cenedese V., Menini A.
core +1 more source
Characterization of TMEM16F-Specific Affibodies and Their Cellular Effects
MembranesThe TMEM16 (Anoctamin) family comprises a group of transmembrane proteins involved in diverse physiological processes, including ion transport and phospholipid scrambling.
Eunyoung Kim +3 more
doaj +1 more source
Mechanisms underlying gastric antral slow waves – a human perspective
The Journal of Physiology, EarlyView.
Dirk F. van Helden
wiley +1 more source