: TMEM16 proteins, also known as anoctamins, are a family of ten membrane proteins with various tissue expression and subcellular localization. TMEM16A (anoctamin 1) is a plasma membrane protein that acts as a calcium-activated chloride channel.
Galietta, Luis Juan Vicente +1 more
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The scramblase Anoctamin 9 controls the immune response of lymphocytes
Functional data from submission:"The scramblase Anoctamin 9 controls the immune response of ...
Kunzelmann, Karl
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, 2015 Purinergic P2X7 receptors (P2X7R) are fundamental to innate immune response. In macrophages, transient stimulation of P2X7R activates several transport mechanisms and induces the scrambling of phospholipids with subsequent membrane blebbing and apoptosis.
Romao, Ana M. +6 more
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Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. [PDF]
, 2015 Calcium-activated chloride channels of the anoctamin (alias TMEM16) protein family fulfill critical functions in epithelial fluid transport, smooth muscle contraction and sensory signal processing.
Daniel Parthier +4 more
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The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels
, 2011 The Ca(2+)-activated Cl(-) channels (CaCCs) are involved in a variety of physiological functions, such as transepithelial anion transport, smooth muscle contraction and olfaction.
Ferrera L. +11 more
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초기 신경발생과정에 관여하는 anoctamin chloride 채널의 역할 [PDF]
, 2012 학위논문 (석사)-- 서울대학교 융합과학기술대학원 : 분자의학 및 바이오제약학과, 2012. 8. 오우택.The embryonic neurogenesis which new neurons are generated in the embryonic brain is critical for the development of the central nervous system.
오정은
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Rhabdomyolysis as an uncommon manifestation of anoctamin-5 muscular dystrophy [PDF]
Background: Anoctamin-5 (ANO5) muscular dystrophy is a rare neuromuscular disease. Muscular weakness and impaired gait may be evident at the moment of diagnosis, serving as defining characteristics of additional muscular dystrophies.
Marta Rodrigues +3 more
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Anoctamin 1 dysregulation alters bronchial epithelial repair in cystic fibrosis [PDF]
, 2013 Cystic fibrosis (CF) airway epithelium is constantly subjected to injury events due to chronic infection and inflammation. Moreover, abnormalities in CF airway epithelium repair have been described and contribute to the lung function decline seen in CF ...
Blouquit-Laye, Sabine +12 more
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Anoctamin 1 antagonism potentiates conventional tocolytic-mediated relaxation of pregnant human uterine smooth muscle. [PDF]
J Physiol Sci, 2021 Hyuga S +8 more
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Bioinformatic Characterization of the Anoctamin Family of Calcium-Activated Chloride Channels and the Establishment of Homology Using Protein Sequence Analysis [PDF]
, 2015 The Anoctamin Family of proteins is closely related to both Transmembrane Channel-like proteins and DUF221 proteins who's functions are largely unknown. These three families are grouped into a larger superfamily called the Anoctamin Superfamily. Here, we
McLaughlin, Daniel
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