Review of the clinical electrooculogram - Part 1: Mechanism of the Light-Rise. [PDF]
Doc OphthalmolConstable PA +3 more
europepmc +1 more source
Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium. [PDF]
Pflugers Arch, 2015 Lee J +15 more
europepmc +1 more source
Association of <i>ANO6</i> gene polymorphism and expression with ankylosing spondylitis in a Chinese Han population. [PDF]
ReumatologiaYang M, Wen X, Wu X, Zhang Y, Gu J.
europepmc +1 more source
Anoctamin 5 as a protective factor in prostate cancer: Insights from WGCNA, machine learning, and experimental analysis, with a focus on the anoctamin family. [PDF]
Transl OncolWang JS +5 more
europepmc +1 more source
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Advances in Anoctamin 1: A Potential New Drug Target in Medicinal Chemistry
Current Topics in Medicinal Chemistry, 2021ANO1, anoctamin 1(also known as TMEM16A), is the molecular basis of calcium-activated chloride channels with ten transmembrane segments which are widely expressed in mammalian cells, including epithelial cells, vascular smooth muscle tissues, electro-excitatory cells, and some tumor cells.
Bing Niu, Xin Cao, Junjie Zhong
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Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells
Biological Chemistry, 2011 Two families of proteins, the bestrophins (Best) and the recently cloned TMEM16 proteins (anoctamin, Ano), recapitulate properties of Ca2+-activated Cl- currents.
Karl Kunzelmann +2 more
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Aerobic training in patients with anoctamin 5 myopathy and hyperckemia
Muscle and Nerve, 2014 INTRODUCTION: Anoctamin 5 deficiency has recently been defined to cause limb-girdle muscular dystrophy type 2L (LGMD2L) with pronounced hyperCKemia. No treatment interventions have been made so far in this condition.METHODS: In 6 patients with LGMD2L, we
John Vissing +2 more
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Anoctamin 1 in secretory epithelia
Cell Calcium, 2014Fluid and electrolyte releasing from secretory epithelia are elaborately regulated by orchestrated activity of ion channels. The activity of chloride channel at the apical membrane decides on the direction and the rate of secretory fluid and electrolyte.
Yongwoo, Jang, Uhtaek, Oh
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Anoctamin 1 expression in the mouse auditory brainstem
Cell and Tissue Research, 2014Calcium-activated chloride channels (CaCCs) are involved in numerous physiological functions, including the epithelial movement of fluid. Anoctamin 1 (ANO1) has recently been cloned and characterized as a CaCC and is known to be expressed in various secretory epithelia and in nervous tissues such as the dorsal root ganglia and retina.
Sang Jae, Cho +4 more
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