Results 171 to 180 of about 5,018 (188)
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Altered anoctamin-1 and tyrosine phosphorylation in congenital ureteropelvic junction obstruction
Journal of Pediatric Surgery, 2020Ureteropelvic junction (UPJ) obstruction is the most common cause of congenital hydronephrosis in children. The pathophysiology of UPJ obstruction and the exact mechanism of pelviureteral peristalsis are poorly understood. Anoctamin-1 (ANO1), a Ca2+-activated chloride channel, has been shown to play a key role in muscle wall contractions in the ...
Manuela, Hunziker +4 more
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Function and Regulation of the Calcium-Activated Chloride Channel Anoctamin 1 (TMEM16A)
2022Various human tissues express the calcium-activated chloride channel Anoctamin 1 (ANO1), also known as TMEM16A. ANO1 allows the passive chloride flux that controls different physiological functions ranging from muscle contraction, fluid and hormone secretion, gastrointestinal motility, and electrical excitability.
Jorge, Arreola +5 more
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Calcium-regulated chloride channel anoctamin-1 is present in the suprachiasmatic nuclei of rats
NeuroReport, 2018Calcium-regulated chloride channel (CaCC) anoctamin-1 has been recently identified in neurons. In neurons, which express the Na-K-2Cl cotransporter, activation of CaCCs increases firing frequency, by reversion between the Cl equilibrium potential and the membrane resting potential, leading to membrane depolarization by Cl extrusion from the cell ...
Raúl, Aguilar-Roblero +7 more
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A mathematical model of the effects of anoctamin-1 loss on intestinal slow wave entrainment
2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2017The interstitial cells of Cajal (ICC) generate electrophysiological events called slow waves that regulate the motility of the gastrointestinal (GI) tract. Recent studies have demonstrated that the Ca2+-activated Cl- -channel, encoded by the anoctamin1 (Ano1) protein, has a major role in regulating intestinal slow waves and motility.
Anna Qian +4 more
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Anoctamin‐like protein 1 regulates repolarization in Paramecium behavioral responses
Journal of Eukaryotic MicrobiologyAbstractParamecium exhibits responsive behavior to environmental changes, moving either closer to or further away from stimuli. Electrophysiological experiments have revealed that these behavioral responses are controlled by membrane potentials. Anoctamin, a Ca2+‐activated Cl− channel, is involved in the regulation of membrane potential in mammals ...
Kana Sakoshita +6 more
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Dilated cardiomyopathy in patients with mutations in anoctamin 5
International Journal of Cardiology, 2013Karim Wahbi, A Behin, F Leturcq
exaly
Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells
Biological Chemistry, 2011Karl Kunzelmann +2 more
exaly
Aerobic training in patients with anoctamin 5 myopathy and hyperckemia
Muscle and Nerve, 2014Nicolai Preisler, John Vissing
exaly