Results 111 to 120 of about 21,690 (286)

Population Pharmacokinetics Modeling of Selpercatinib to Support Posology in Pediatric Patients With RET‐Altered Metastatic Thyroid Cancer or Solid Tumors

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Selpercatinib is a first‐in‐class, highly selective, RET kinase inhibitor with CNS activity, approved for the treatment of RET‐altered lung, thyroid, and other cancers. We report pharmacokinetic analyses to identify factors affecting selpercatinib steady‐state exposure and support posology in pediatric patients.
Dan Liu, Jan‐Stefan van der Walt
wiley   +1 more source

Evaluation of Co-Administration of Omperazole with H2 Blockers and Antacids

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2007
Introduction: Omperazole as a very useful drug in peptic ulcer which needs to be converted to active form and its activation requires acidic enviornments.
S Bashir, H Salman Roughani, A Babaei
doaj  

Association between Antacid Exposure and Risk of Interstitial Lung Diseases [PDF]

open access: yesTuberculosis and Respiratory Diseases
Background The mechanisms leading to lung fibrosis are still under investigation. This study aimed to demonstrate whether antacids could prevent the development of interstitial lung disease (ILD).
Soohyun Bae   +5 more
doaj   +1 more source

ABC of sexually transmitted infections - Main presentations of sexually transmitted infections in men [PDF]

open access: yes, 2004
This article is adapted from the fifth edition of the ABC ofSexually Transmitted Diseases, which is published by BMJBooks (www.bmjbooks.com).Some sexually transmitted infections, such as gonorrhoea and chlamydial infection, have different presentations ...
Richens, J
core  

Exposing and Challenging “Grit” in Physics Education

open access: yesScience Education, EarlyView.
ABSTRACT In STEM education, grit is increasingly the focus of research, with scholars and educators seeking to develop and test interventions that will enhance persistence. As part of the special issue Centering Affect and Emotion Toward Justice and Dignity in Science Education, in this paper, we use interviews with 12 white physics faculty to show ...
Amy Robertson   +3 more
wiley   +1 more source

Drug Related Esophagitis

open access: yesCanadian Journal of Gastroenterology, 1989
Esophageal injury after ingestion of various drugs often goes unrecognized. Two cases of tetracycline induced esophagitis are reported. The main presenting symptoms were odynophagia and dysphagia for both solids and liquids following the first two or ...
René Beaudry, Franco Colizza
doaj   +1 more source

Surface Localized Coacervation Controlled by Bioactive Nanoarchitectonic Polyelectrolyte Multilayers

open access: yesSmall, EarlyView.
Using enzymatically active nanoarchitectured polyelectrolyte multilayers (PEMs), localized liquid–liquid phase separation can be directed from a so‐modified surface. In the presence of urea, PEM‐containing urease layers generate a pH gradient near the surface resulting in the self‐coacervation of a model peptide‐based coacervator.
Jean‐Yves Runser   +10 more
wiley   +1 more source

A combination of carbonates and Opuntia ficus-indica extract protects esophageal cells against simulated acidic and non-acidic reflux in vitro

open access: yesScientific Reports
Buffering of stomach acid by antacids is a well-established symptomatic therapy for heartburn. In addition, preparations from prickly pear (Opuntia ficus-indica) have been shown to reduce tissue damage in experimental gastritis models and to attenuate ...
Martin D. Lehner   +2 more
doaj   +1 more source

Optimasi Starch 1500® Dan Crospovidone Pada Formulasiorally Disintegrating Tablet (Odt) Antasida [PDF]

open access: yes, 2017
SARI Gastritis atau secara umum dikenal dengan istilah sakit “maag” ialah peradangan pada dinding lambung terutama pada selaput lendir lambung.Penyakit gastritis umumya diatasi dengan penggunaan antasida yang merupakan kombinasi antara Aluminium ...
Ananthi, D. G. (Dea)   +2 more
core  

Defective Antifluorite MnO2‐Layered RuO2 for Direct Seawater Electrolysis at Circum‐Neutral pH

open access: yesSmall, EarlyView.
A defective antifluorite MnO2 overlayer that enables nearly 100% oxygen selectivity in direct seawater electrolysis at neutral pH is reported. Combining experimental validation and DFT simulations, this work reveals how a unique Mn–O framework blocks chloride while maintaining OER activity—offering a robust and scalable solution for green hydrogen ...
Nan‐Nan Liang   +7 more
wiley   +1 more source

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