Results 261 to 270 of about 919,029 (311)
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Cardiology, 1985
At present nitrates remain the initial treatment for relief or prevention of angina in patients with coronary artery disease. In cases where nitrates and beta blockers have been used and are ineffective for managing effort angina, calcium antagonists may be substituted or added to the beta-blocking treatment. When the predominant symptom is rest angina,
C R, Conti +3 more
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At present nitrates remain the initial treatment for relief or prevention of angina in patients with coronary artery disease. In cases where nitrates and beta blockers have been used and are ineffective for managing effort angina, calcium antagonists may be substituted or added to the beta-blocking treatment. When the predominant symptom is rest angina,
C R, Conti +3 more
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1966
Publisher Summary Vitamin K activity is shared by a fairly large number of compounds. They consist, in the main, of two naturally occurring groups of compounds: phylloquinones (K), containing saturated isoprenoid side chains, and menaquinones (MK) with unsaturated isoprenoid side chains.
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Publisher Summary Vitamin K activity is shared by a fairly large number of compounds. They consist, in the main, of two naturally occurring groups of compounds: phylloquinones (K), containing saturated isoprenoid side chains, and menaquinones (MK) with unsaturated isoprenoid side chains.
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Letters in Applied Microbiology, 1994
Three groups of substances were identified which inhibit the bactericidal activity of bacitracin. Beside two divalent metals, Mg2+ and Ca2+, and a metabolite with chelating properties, citrate, the most pronounced effect was observed with pyrophosphate. Metals probably prevent access of bacitracin to the lipid carrier whereas metabolites with chelating
Z, Podlesek, A, Comino
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Three groups of substances were identified which inhibit the bactericidal activity of bacitracin. Beside two divalent metals, Mg2+ and Ca2+, and a metabolite with chelating properties, citrate, the most pronounced effect was observed with pyrophosphate. Metals probably prevent access of bacitracin to the lipid carrier whereas metabolites with chelating
Z, Podlesek, A, Comino
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Hormone and Metabolic Research, 1986
The three classes of CCK antagonists illustrate the various factors governing affinity of the antagonists for the CCK receptor. The major influence in determining potency of the cyclic nucleotide derivatives, amino acid derivatives and C-terminal fragments of CCK, are hydrophobic forces.
P N, Maton, R T, Jensen, J D, Gardner
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The three classes of CCK antagonists illustrate the various factors governing affinity of the antagonists for the CCK receptor. The major influence in determining potency of the cyclic nucleotide derivatives, amino acid derivatives and C-terminal fragments of CCK, are hydrophobic forces.
P N, Maton, R T, Jensen, J D, Gardner
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European Heart Journal, 1980
Drugs which interfere with the voltage-activated inward displacement of calcium ions into excitable cells, including those of the myocardium, atrial and ventricular nodes, and smooth muscle cells, have become known as calcium antagonists. These drugs are a heterogeneous group, and differ from one another in chemistry, tissue specificity, potency and ...
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Drugs which interfere with the voltage-activated inward displacement of calcium ions into excitable cells, including those of the myocardium, atrial and ventricular nodes, and smooth muscle cells, have become known as calcium antagonists. These drugs are a heterogeneous group, and differ from one another in chemistry, tissue specificity, potency and ...
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Cellular and Molecular Life Sciences, 2006
Effects of vasopressin via V1a- and V2-receptors are closely implicated in a variety of water-retaining diseases and cardiovascular diseases, including heart failure, hyponatraemia, hypertension, renal diseases, syndrome of inappropriate antidiuretic hormone secretion, cirrhosis and ocular hypertension.
Lemmens, Rosa, Kamyar, Majid-Reza
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Effects of vasopressin via V1a- and V2-receptors are closely implicated in a variety of water-retaining diseases and cardiovascular diseases, including heart failure, hyponatraemia, hypertension, renal diseases, syndrome of inappropriate antidiuretic hormone secretion, cirrhosis and ocular hypertension.
Lemmens, Rosa, Kamyar, Majid-Reza
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2013
Kisspeptin is now known to be an important regulator of the hypothalamic--pituitary-gonadal axis and is the target of a range of regulators, such as steroid hormone feedback, nutritional and metabolic regulation. Kisspeptin binds to its cognate receptor, KISS1R (also called GPR54), on GnRH neurons and stimulates their activity, which in turn provides ...
Antonia Kathryn, Roseweir +1 more
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Kisspeptin is now known to be an important regulator of the hypothalamic--pituitary-gonadal axis and is the target of a range of regulators, such as steroid hormone feedback, nutritional and metabolic regulation. Kisspeptin binds to its cognate receptor, KISS1R (also called GPR54), on GnRH neurons and stimulates their activity, which in turn provides ...
Antonia Kathryn, Roseweir +1 more
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Expert Opinion on Biological Therapy, 2001
The majority of cancer have an absolute requirement for angiogenesis, the process by which new blood vessels are formed. The most potent angiogenic cytokine is vascular endothelial growth factor (VEGF) and there has been substantial research into the development of VEGF/VEGF receptor (VEGFR) antagonists.
Hasan, J +1 more
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The majority of cancer have an absolute requirement for angiogenesis, the process by which new blood vessels are formed. The most potent angiogenic cytokine is vascular endothelial growth factor (VEGF) and there has been substantial research into the development of VEGF/VEGF receptor (VEGFR) antagonists.
Hasan, J +1 more
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Australian and New Zealand Journal of Medicine, 1984
The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
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The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
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Antagonists to the benzodiazepines
British Dental Journal, 1984P, McGonigal, C N, Schofield
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