Results 241 to 250 of about 919,029 (311)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Evaluation of Indigo Naturalis Prepared Using a Novel Method: Anti-Inflammatory Activities Against Colonic Cancer Cell Lines. [PDF]

Mediators Inflamm
Xu X, Lin L, Ning W, Zhou X, Ullah A, Huang X, Yang H, Wu X, Diao Y.   +8 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The mechanism of different microglial receptors mediating central inflammation in chronic migraine: a meta-analysis. [PDF]

J Headache Pain
Lin X, Yu W, Lou J, Cao Z, Song W.
europepmc   +1 more source

Screening-detected refractive errors in infants born after assisted reproductive technology: a prospective cohort study. [PDF]

Arch Gynecol Obstet
Zou X, Jalloh MA, Wang Z, Zong Y, Jiang Y, Jiang T, You L, Qin R, Lv H, Liu Y, Sun T, Xu B, Han X, Liu X, Zhou K, Jin G, Ma H, Lin Y, Hu Z, Liu H, Du J, Li J.   +21 more
europepmc   +1 more source

Impulsivity in NrCAM KO Mice Is Reduced by NMDAR Antagonist MK-801 but Not by AMPAR Antagonist CNQX. [PDF]

NeuroSci
Buhusi M, Buhusi CV.
europepmc   +1 more source

Tumor growth inhibitory activity of the P2X7 receptor antagonist AZ10606120 in two cell lines of human glioblastoma. [PDF]

Purinergic Signal
Graziano M, Bono S, Pizzoferrato M, Ferraro C, Grossi F, Navarra P, Martire M, Lisi L.   +7 more
europepmc   +1 more source

Identification of Dopamine D2 Receptor as a Direct Target of Salidroside and Tyrosol by Integrated Transcriptomic and Biophysical Approaches. [PDF]

Pharmaceuticals (Basel)
Zhang J, Lin K, Jiang C, Zheng J, Huang H, Han J.   +5 more
europepmc   +1 more source

Galanin Receptors in the Central Nervous System: Exploring Ligand Interactions, Signal Transduction, and Potential Clinical Implications. [PDF]

Molecules
Owczarek A, Blecharz-Klin K.
europepmc   +1 more source