Results 221 to 230 of about 471,515 (268)
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European Heart Journal, 1980
Drugs which interfere with the voltage-activated inward displacement of calcium ions into excitable cells, including those of the myocardium, atrial and ventricular nodes, and smooth muscle cells, have become known as calcium antagonists. These drugs are a heterogeneous group, and differ from one another in chemistry, tissue specificity, potency and ...
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Drugs which interfere with the voltage-activated inward displacement of calcium ions into excitable cells, including those of the myocardium, atrial and ventricular nodes, and smooth muscle cells, have become known as calcium antagonists. These drugs are a heterogeneous group, and differ from one another in chemistry, tissue specificity, potency and ...
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Cellular and Molecular Life Sciences, 2006
Effects of vasopressin via V1a- and V2-receptors are closely implicated in a variety of water-retaining diseases and cardiovascular diseases, including heart failure, hyponatraemia, hypertension, renal diseases, syndrome of inappropriate antidiuretic hormone secretion, cirrhosis and ocular hypertension.
Lemmens, Rosa, Kamyar, Majid-Reza
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Effects of vasopressin via V1a- and V2-receptors are closely implicated in a variety of water-retaining diseases and cardiovascular diseases, including heart failure, hyponatraemia, hypertension, renal diseases, syndrome of inappropriate antidiuretic hormone secretion, cirrhosis and ocular hypertension.
Lemmens, Rosa, Kamyar, Majid-Reza
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2013
Kisspeptin is now known to be an important regulator of the hypothalamic--pituitary-gonadal axis and is the target of a range of regulators, such as steroid hormone feedback, nutritional and metabolic regulation. Kisspeptin binds to its cognate receptor, KISS1R (also called GPR54), on GnRH neurons and stimulates their activity, which in turn provides ...
Antonia Kathryn, Roseweir +1 more
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Kisspeptin is now known to be an important regulator of the hypothalamic--pituitary-gonadal axis and is the target of a range of regulators, such as steroid hormone feedback, nutritional and metabolic regulation. Kisspeptin binds to its cognate receptor, KISS1R (also called GPR54), on GnRH neurons and stimulates their activity, which in turn provides ...
Antonia Kathryn, Roseweir +1 more
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Expert Opinion on Biological Therapy, 2001
The majority of cancer have an absolute requirement for angiogenesis, the process by which new blood vessels are formed. The most potent angiogenic cytokine is vascular endothelial growth factor (VEGF) and there has been substantial research into the development of VEGF/VEGF receptor (VEGFR) antagonists.
Hasan, J +1 more
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The majority of cancer have an absolute requirement for angiogenesis, the process by which new blood vessels are formed. The most potent angiogenic cytokine is vascular endothelial growth factor (VEGF) and there has been substantial research into the development of VEGF/VEGF receptor (VEGFR) antagonists.
Hasan, J +1 more
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Nature, 1969
IF drugs b and c are competitive antagonists of drug a, then it would seem self evident that the addition of c to a system in which b was already present would increase the degree of block. But where the receptors are exposed to the agonist for only a short time there is another possibility. If the first antagonist dissociates from the receptors slowly,
R P, Stephenson, B L, Ginsborg
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IF drugs b and c are competitive antagonists of drug a, then it would seem self evident that the addition of c to a system in which b was already present would increase the degree of block. But where the receptors are exposed to the agonist for only a short time there is another possibility. If the first antagonist dissociates from the receptors slowly,
R P, Stephenson, B L, Ginsborg
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Australian and New Zealand Journal of Medicine, 1984
The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
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The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
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Antagonists to the benzodiazepines
British Dental Journal, 1984P, McGonigal, C N, Schofield
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2007
Androgens are essential for the development and maintenance of male sexual characteristics. They exert their effects through the androgen receptor, which is a member of the …
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Androgens are essential for the development and maintenance of male sexual characteristics. They exert their effects through the androgen receptor, which is a member of the …
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