Results 21 to 30 of about 910,715 (290)

Filling the Gaps in Antagonist CCR5 Binding, a Retrospective and Perspective Analysis

Frontiers in Immunology, 2022
The large number of pathologies that position CCR5 as a central molecular determinant substantiates the studies aimed at understanding receptor-ligand interactions, as well as the development of compounds that efficiently block this receptor.
Yerkezhan Amerzhanova, Luca Vangelista
doaj   +1 more source

α_1L-adrenoceptors mediate contraction of human erectile tissue [PDF]

, 2018
α1-adrenoceptor antagonists can impact upon sexual function and have potential in the treatment of erectile dysfunction. Human erectile tissue contains predominantly α1A-adrenoceptors, and here we examined whether contractions of this tissue are mediated
Campbell, Alistair, Chapple, Christopher R., Chess-Williams, Russ, Davis, Beverley J., Naylor, Alisdair L., Sellers, Donna J., Sillar, David   +6 more
core   +1 more source

Inhibitory effects of antagonistic bacteria inhabiting the rhizosphere of the sugarbeet plants, on Cercospora beticola Sacc., the causal agent of Cercospora leaf spot disease on sugarbeet

Journal of Plant Protection Research, 2016
In the present study, the antagonistic capability of bacterial agents inhabiting the rhizosphere of sugarbeet plants were evaluated against Cercospora beticola Sacc. under laboratory and greenhouse conditions.
Arzanlou Mahdi, Mousavi Somayeh, Bakhshi Mounes, Khakvar Reza, Bandehagh Ali   +4 more
doaj   +1 more source

Insight into a Successful Development of Biocontrol Agents: Production, Formulation, Packaging, and Shelf Life as Key Aspects

Horticulturae, 2022
Biocontrol agents (BCAs) have been proposed and studied over recent decades as a suitable alternative to diminish or substitute synthetic fungicides used to control pre- and postharvest diseases.
Neus Teixidó, Josep Usall, Rosario Torres   +2 more
doaj   +1 more source

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]

, 2013
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre, Liposits, Zsolt, Sárvári, Miklós, Vastagh, Csaba   +3 more
core   +9 more sources

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma, Kennedy, Charles, Tasker, Paul N., Westfall, Timothy D.   +3 more
core   +1 more source

Efektivitas Isolat Bakteri dari Rizosfer dan Bahan Organik Terhadap Ralstonia solanacearum dan Fusarium oxysporum pada Tanaman Kentang

Jurnal Fitopatologi Indonesia, 2014
Rhizosphere is an ideal area for growth and development of microbial antagonists, because it is a nutrition rich area. Nutrients that secreted in the rhizosphere are influenced by many environmental factors which in turn effect the diversity and ...
Tutik Kuswinanti, Baharuddin Baharuddin, Sri Sukmawati   +2 more
doaj   +1 more source

Sleep-promoting activity of lotus (Nelumbo nucifera) rhizome water extract via GABAA receptors

Pharmaceutical Biology, 2022
Context The sleep-promoting activity of Nelumbo nucifera Gaertn. (Nymphaeaceae) alkaloids in leaves or seeds are well known. However, the sleep-promoting activity of the lotus rhizome (LE), which is used mainly as food, has not yet been evaluated ...
Yejin Ahn, Singeun Kim, Chunwoong Park, Jung Eun Kim, Hyung Joo Suh, Kyungae Jo   +5 more
doaj   +1 more source

Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]

, 1993
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer, Alzheimer, Alzheimer, Alzheimer, Andreasen, Arai, Ault, Ault, B. Sutor, Bauer, Beavo, Beavo, Ben-Ari, Bruns, Bruns, C. Alzheimer, Chamberlin, Daly, Dragunow, Dragunow, Dunwiddie, Dunwiddie, Dunwiddie, Fredholm, G. Ten Bruggencate, Gerber, Greene, Greene, Haas, Hablitz, Hablitz, Jackisch, Johnston, Linden, Linden, Llinás, Lohse, Madison, Malenka, Meghji, Miles, Moraidis, Nicholson, Pockett, Prestwich, Prince, Scholz, Schubert, Schubert, Smellie, Smellie, Smith, Snyder, Snyder, Sutor, Tanaka, Thompson, Thompson, Van Calker, Williams, Zetterström   +60 more
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Untargeted Metabolomics Reveals the Potential Antidepressant Activity of a Novel Adenosine Receptor Antagonist

Molecules, 2022
Depression is the most common mental illness, affecting approximately 4.4% of the global population. Despite many available treatments, some patients exhibit treatment-resistant depression.
Arnold Petrus Smith, Jeremie Zander Lindeque, Mietha Magdalena van der Walt   +2 more
doaj   +1 more source