Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
GPCRact: a hierarchical framework for predicting ligand-induced GPCR activity via allosteric communication modeling. [PDF]
Son H, Yi GS.
europepmc +1 more source
Identifying androgen receptor antagonists using a metabolically competent high-throughput screening assay. [PDF]
Lynch C +5 more
europepmc +1 more source
Factors influencing oocyte yield and embryo quality in donor IVF cycles: a retrospective cohort study. [PDF]
Lin PY +7 more
europepmc +1 more source
GnRH antagonist protocol versus long-acting GnRH agonist protocol on pregnancy outcomes in IVF/ICSI: a retrospective cohort study. [PDF]
Zhao P +7 more
europepmc +1 more source
Corrigendum: A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies. [PDF]
Freie B +6 more
europepmc +1 more source
Chewing loads alter TMJ metabolism and Zn homeostasis via PIEZO1/ TRPV4. [PDF]
Wang Y +6 more
europepmc +1 more source

