Results 81 to 90 of about 172,666 (300)

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

open access: yesAdvanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang   +7 more
wiley   +1 more source

The neural correlates of desire. [PDF]

open access: yesPLoS ONE, 2008
In an event-related fMRI study, we scanned eighteen normal human subjects while they viewed three categories of pictures (events, objects and persons) which they classified according to desirability (desirable, indifferent or undesirable).
Hideaki Kawabata, Semir Zeki
doaj   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Morphologic asymmetry of the human anterior cingulate cortex

open access: yesNeuroImage, 2007
The anterior cingulate cortex (ACC) is thought to play a major role in executive processes. Studies assessing neuroanatomical attributes of this region report a high degree of morphological variability. Recent theories consider the fissurization of the cortex to be a product of gross mechanical processes related to cortical growth and local ...
Rene J, Huster   +4 more
openaire   +2 more sources

The Dorsal Anterior Cingulate Cortex Modulates Dialectical Self-Thinking [PDF]

open access: yesFrontiers in Psychology, 2016
Dialectical self-thinking involves holding the view that one can possess contradictory traits such as extraverted and introverted. Prior work has demonstrated that the dorsal part of anterior cingulate cortex (dACC) plays a crucial role in conflict monitoring as well as self-related processing.
Fei eWang   +11 more
openaire   +3 more sources

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

The distressed brain: a group blind source separation analysis on tinnitus. [PDF]

open access: yesPLoS ONE, 2011
Tinnitus, the perception of a sound without an external sound source, can lead to variable amounts of distress.In a group of tinnitus patients with variable amounts of tinnitus related distress, as measured by the Tinnitus Questionnaire (TQ), an ...
Dirk De Ridder   +2 more
doaj   +1 more source

Mapping the functional connectivity of anterior cingulate cortex

open access: yesNeuroImage, 2007
Anterior cingulate cortex (ACC) is a nexus of information processing and regulation in the brain. Reflecting this central role, ACC is structurally and functionally heterogeneous, a fact long appreciated in studies of non-human primates. Human neuroimaging studies also recognize this functional heterogeneity, with meta-analyses and task-based studies ...
Daniel S, Margulies   +5 more
openaire   +2 more sources

Bilingualism Tunes the Anterior Cingulate Cortex for Conflict Monitoring [PDF]

open access: yesCerebral Cortex, 2011
Monitoring and controlling 2 language systems is fundamental to language use in bilinguals. Here, we reveal in a combined functional (event-related functional magnetic resonance imaging) and structural neuroimaging (voxel-based morphometry) study that dorsal anterior cingulate cortex (ACC), a structure tightly bound to domain-general executive control ...
ABUTALEBI , JUBIN   +7 more
openaire   +3 more sources

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

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