Results 61 to 70 of about 9,072 (226)

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Mitochondrial Dysfunction in Patients With Nonarteritic Anterior Ischemic Optic Neuropathy and Optic Disc Drusen

, 2022
The anterior optic nerve is packed with mitochondria to generate energy to support action potential conduction. Mitochondrial dysfunction leads to vision loss in dominant optic atrophy (DOA) and Leber hereditary optic neuropathy, and has been implicated ...
Homer Chiang; Aditi Swarup; Chinyere Iweka; Louise Mesentier-Louro; Sangeetha Pugazhendhi; Ajay Kumar; Katrin Andreasson; Albert Wu; Yaping Joyce Liao
core  

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

Journal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva, Jordana Gaudie Gurian, Isabella Mesquita Venâncio, Eva Carolina Rocha, Gisele Sampaio Silva   +4 more
wiley   +1 more source

Oxidative Stress: A Suitable Therapeutic Target for Optic Nerve Diseases?

Antioxidants, 2023
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve.
Francesco Buonfiglio, Elsa Wilma Böhm, Norbert Pfeiffer, Adrian Gericke   +3 more
doaj   +1 more source

Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy.

JAMA Ophthalmol
Cai CX, Hribar M, Baxter S, Goetz K, Swaminathan SS, Flowers A, Brown EN, Toy B, Xu B, Chen J, Chen A, Wang S, Lee C, Leng T, Ehrlich JR, Barkmeier A, Armbrust KR, Boland MV, Dorr D, Boyce D, Alshammari T, Swerdel J, Suchard MA, Schuemie M, Bu F, Sena AG, Hripcsak G, Nishimura A, Nagy P, Falconer T, DuVall SL, Matheny M, Viernes B, O'Brien W, Zhang L, Martin B, Westlund E, Mathioudakis N, Fan R, Wilcox A, Lai A, Stocking JC, Takkouche S, Lee LH, Xie Y, Humes I, McCoy DB, Adibuzzaman M, Areaux RG, Rojas-Carabali W, Brash J, Lee DA, Weiskopf NG, Mawn L, Agrawal R, Morgan-Cooper H, Desai P, Ryan PB.   +57 more
europepmc   +3 more sources

The Flail Limb Syndrome

Muscle &Nerve, EarlyView.
ABSTRACT The flail limb syndrome is primarily a lower motor neuron disorder that initially affects proximal arm muscles (flail arm syndrome—FAS) or distal leg muscles (flail leg syndrome—FLS). Both were recognized early on (1886 for FAS and 1918 for FLS) as somewhat distinct from classic amyotrophic lateral sclerosis (ALS).
Mark B. Bromberg
wiley   +1 more source

Non-arteritic anterior ischemic optic neuropathy secondary to acute primary-angle closure

, 2013
Ajay E Kuriyan, Byron L Lam Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA Purpose: To describe a case of non-arteritic ischemic optic neuropathy (NAION) secondary to acute primary-angle closure (APAC). Methods: Case report.
Lam, Byron L, Kuriyan, Ajay E, Lam BL, Kuriyan AE   +3 more
core   +1 more source

Evaluating the Evolving Real‐World Adverse Events of GLP‐1RAs Using FDA Adverse Event Reporting System (FAERS)

Obesity, EarlyView.
Web portal for interrogating Adverse Events of GLP‐1 RA in diabetes vs weight control/obesity. ABSTRACT Objective This study aimed to assess the spectrum and frequency of adverse events (AEs) linked to glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) using the US FDA Adverse Event Reporting System (FAERS).
David Stone, Mary Playdon, Stephen D. Hursting, Aik Choon Tan   +3 more
wiley   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Sequential development of non-arteritic anterior ischemic optic neuropathy in a patient on hemodialysis

, 2017
Purpose: Non-arteritic anterior ischemic optic neuropathy (NA-AION) is typically a disorder of patients 50 years and older predisposed to the vascular and structural optic disc risk factors.
Jain, M, Parchand, MS, Babu, KR, Srinivasan, R   +3 more
core   +1 more source