Results 91 to 100 of about 4,599,290 (296)

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

open access: yesAdvanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan   +9 more
wiley   +1 more source

Treatment of Cerebrospinal Fluid leakage in Skull Base Surgery [PDF]

open access: yes, 2008
Objective : In various skull base approaches, the risk of cerebrospinal fluid (CSF) leakage exists and the leakage may lead to a life-threatening condition such as meningoencephalitis.
안정용   +4 more
core  

HIV Presenting as Inflammatory Pseudotumor of the Skull Base: Case Report and Review of the Literature

open access: yes, 2013
A 52-year-old woman presented with frontal headaches, panhypopituitarism, and right cranial nerve VI palsy. MRI of the brain with gadolinium revealed a destructive process involving the clivus and bilateral petrous apices, and extending into bilateral ...
Sargi, Zoukaa B   +2 more
core   +1 more source

Case Series of Skull Base Meningioma Resection in the Octogenarian Population

open access: yes, 2021
Introduction  The geriatric population is the fastest growing segment of the American population, and octogenarians are increasingly seen by neurosurgeons for relatively common lesions such as meningiomas.
Dabecco, Rocco   +3 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Purely Endoscopic Keyhole Supraorbital Approaches for Anterior and Middle Skull Base Tumors

open access: yes, 2013
Anterior and middle skull base tumors, mainly meningiomas, are usually operated on using a sub-frontal route with a microscope. With modern radiotherapy, the goal of skull base surgery moves from a radical surgery with high rate of side effect to a ...
Messerer, M.   +7 more
core  

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu   +7 more
wiley   +1 more source

Systematic Analysis of Cerebrospinal Fluid Leak after Endoscopic Skull Base Surgery: Tumor Location, Closure Method, and Pathology.

open access: yes, 2011
Objective: Endoscope-assisted cranial base surgery provides a direct, minimally invasive alternative to traditional transcranial approaches. One of the greatest challenges of endoscopic anterior base surgery is avoidance of postoperative CSF leaks, which
Theodore Schwartz   +9 more
core   +1 more source

Advance on endoscopic skull base surgery

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2019
Endoscopic skull base surgery started from 1990s, and has undergone fast development in the past 20 years. It has involved various skull base regions from the anterior skull base to the craniovertebral junction (CVJ) and jugular foramen, including intra-
Qiu-hang ZHANG
doaj  

A Ciliary Protein EVC2/LIMBIN Plays a Critical Role in the Skull Base for Mid-Facial Development

open access: yesFrontiers in Physiology, 2018
Ellis-van Creveld (EvC) syndrome is an autosomal recessive chondrodysplastic disorder. Affected patients present a wide spectrum of symptoms including short stature, postaxial polydactyly, and dental abnormalities.
Anshul K. Kulkarni   +7 more
doaj   +1 more source

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