Results 101 to 110 of about 4,599,290 (296)

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Microvascular tissue transfer in reconstruction of anterior skull base defects secondary to sinonasal malignancies: a case series and proposed reconstructive framework

Egyptian Journal of Neurosurgery
Sinonasal malignancies such as lymphoepithelial carcinoma (LEC) and esthesioneuroblastoma (ENB) are rare but aggressive neoplasms that frequently necessitate extensive resection of anterior skull base structures, creating complex defects.
Nikhil Prasad, Kripa Shankar Mishra, Rajan Arora, Anchit Kumar, Samarth Gupta, Sourav Sarkar   +5 more
doaj   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Identification of Risk Factors for Complication in Those Undergoing Anterior Cranial Base Surgery

, 2009
Craniofacial resection is the gold standard for resection of tumors of the paranasal sinuses and anterior skull base. This procedure was described approximately 50 years ago, and despite advances in technique, imaging, and endoscopy, as well as the ...
Liang, Jonathan, Newman, Jason G, O'Malley, Bert W, Cohen, Marc A, Leibowitz, Jason M   +4 more
core   +1 more source

Refining the Indications for the Addition of Orbital Osteotomy during Anterior Cranial Base Approaches: Morphometric and Radiologic Study of the Anterior Cranial Base Osteology

Journal of Neurological Surgery Reports, 2014
Objectives In anatomic and radiologic morphometric studies, we examine a predictive method, based on preoperative imaging of the anterior cranial base, to define when addition of orbital osteotomy is warranted.
Juan Carlos DeBattista, Norberto Andaluz, Mario Zuccarello, Robert G. Kerr, Jeffrey T. Keller   +4 more
doaj   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Bilateral External Auditory Canal Cholesteatoma Invading Skull Base [PDF]

, 2006
External auditory canal cholesteatoma is an uncommon lesion of the external auditory canal, which usually present with otorrhea and chronic dull pain. It usually eroded bony portion of external auditory canal wall extensively with progressive bony lysis,
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Morphometry relevant to anterior petrosectomy with special reference to Kawase’s triangle

National Journal of Clinical Anatomy, 2017
Background and aims : The petrous apex and the middle cranial fossa is a commonly explored area in neurosurgeries and hence require a holistic approach which should include the possibility of anatomical variants and morphometric dissimilarities. Material
Abu Ubaida Siddiqui, Bikash Chandra Satapathy, Sukhjeet Singh Gill   +2 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source