Results 11 to 20 of about 84,091 (345)

Anthelmintic Resistance and Its Mechanism: A Review

Infection and Drug Resistance, 2021
Workye Fissiha,1 Mebrie Zemene Kinde2 1Department of Epidemiology and Public Health, College of Veterinary Medicine and Animal Sciences, University of Gondar, Gondar, Amhara Regional State, Ethiopia; 2Department of Veterinary Biomedical Sciences, College
Fissiha W, Kinde MZ
doaj   +2 more sources

Identification of Fromiamycalin and Halaminol A from Australian Marine Sponge Extracts with Anthelmintic Activity against Haemonchus contortus

Marine Drugs, 2019
There is an urgent need to discover and develop new anthelmintics for the treatment of parasitic nematodes of veterinary importance to circumvent challenges linked to drug resistant parasites.
H. M. P. Dilrukshi Herath, Sarah Preston, Abdul Jabbar, Jose Garcia-Bustos, Aya C. Taki, Russell S. Addison, Sasha Hayes, Karren D. Beattie, Sean L. McGee, Sheree D. Martin, Merrick G. Ekins, John N. A. Hooper, Bill C. H. Chang, Andreas Hofmann, Rohan A. Davis, Robin B. Gasser   +15 more
doaj   +2 more sources

Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity [PDF]

PLoS Neglected Tropical Diseases, 2019
The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the appearance of drug resistant nematodes, there is a need to develop novel compounds, among which
Guillermina Hernando, Ornella Turani, C. Bouzat   +2 more
semanticscholar   +3 more sources

Exploring the Anthelmintic, Antioxidant, and Cytotoxic Potential of <i>Khaya grandifoliola</i> and <i>Faidherbia albida</i> Extract Combinations: In Vitro Studies on <i>Heligmosomoides polygyrus</i> and <i>Caenorhabditis elegans</i>. [PDF]

J Parasitol Res
Background Soil‐transmitted helminth infection is endemic in Chad and constitutes a public health problem, particularly among school‐age children. The aim of this study was to evaluate the synergistic anthelmintic activity of the combined extracts of Khaya grandifoliola and Faidherbia albida used in Chad by traditional practitioners for the treatment ...
Cédric Y, Nadia NAC, Christalin B, Azizi MA, Kevin TDA, Payne VK, Hu H.   +6 more
europepmc   +2 more sources

Anthelmintic Effect of Chitosan-Encapsulated Bromelain on Gastrointestinal Nematodes in Naturally Infected Goats in Kenya. [PDF]

J Parasitol Res
The emergence of anthelmintic resistance calls for the development of alternatives, including medicinal plant extracts. The present study was aimed at assessing the efficacy of chitosan‐encapsulated bromelain (EB) as an oral solution drug against GIN in goats.
Daïba AR, Adoum IY, Ngotho M, Kagira JM, Maina N.   +4 more
europepmc   +2 more sources

Anthelmintic resistance: is a solution possible?

Experimental parasitology, 2021
A. Ahuir-Baraja, F. Cibot, L. Llobat, M. M. Garijo   +3 more
semanticscholar   +3 more sources

Anthelmintic resistance in soil-transmitted helminths: One-Health considerations

Parasitology Research, 2023
The One-Health approach recognizes the intricate connection between human, animal, and environmental health, and that cooperative effort from various professionals provides comprehensive awareness and potential solutions for issues relating to the health
A. I. Ng'etich, I. Amoah, F. Bux, S. Kumari   +3 more
semanticscholar   +1 more source

Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans wild strains

PLoS Pathogens, 2023
Treatment of parasitic nematode infections in humans and livestock relies on a limited arsenal of anthelmintic drugs that have historically reduced parasite burdens.
Amanda O. Shaver, J. Wit, C. Dilks, Timothy A. Crombie, Hanchen Li, R. Aroian, Erik C. Andersen   +6 more
semanticscholar   +1 more source

Cost-benefit ratio of anthelmintic treatment and its comparative efficacy in commercial dairy farms

Frontiers in Veterinary Science, 2022
Intestinal parasitic infection is one of the major challenges in obtaining optimal production and maintaining the health and welfare of all animals including cattle and buffaloes. Anti-parasitic treatments appear to be a reliable countermeasure. However,
Muhammad Rashid, Naveed Zahra, Amna Chudhary, Tauseef Ur Rehman, Muhammad Tahir Aleem, Abdulaziz Alouffi, Aymen Mohammed, Muhammad Imran Rashid, Muhammad Ehsan, Muhammad Irfan Malik, Ghulam Hussain Dilber, Amir Bakhsh, Mashal M. Almutairi   +12 more
doaj   +1 more source

High Throughput Screening of the NatureBank ‘Marine Collection’ in a Haemonchus Bioassay Identifies Anthelmintic Activity in Extracts from a Range of Sponges from Australian Waters

Molecules, 2021
Widespread resistance in parasitic nematodes to most classes of anthelmintic drugs demands the discovery and development of novel compounds with distinct mechanisms of action to complement strategic or integrated parasite control programs.
Aya C. Taki, Joseph J. Byrne, Abdul Jabbar, Kah Yean Lum, Sasha Hayes, Russell S. Addison, Kelsey S. Ramage, Andreas Hofmann, Merrick G. Ekins, Tao Wang, Bill C. H. Chang, Rohan A. Davis, Robin B. Gasser   +12 more
doaj   +1 more source