Results 11 to 20 of about 41,721 (252)

Analysis, Occurrence and Exposure Evaluation of Antibiotic and Anthelmintic Residues in Whole Cow Milk from China

Antibiotics, 2023
An optimized QuEChERS method for the simultaneous extraction of 26 antibiotics and 19 anthelmintics in whole cow milk was established, followed by UHPLC-MS/MS analysis. Briefly, 20 mL acetonitrile with 1 g disodium hydrogen citrate, 2 g sodium citrate, 4
Liming Chang, Sishi Du, Xiaojiao Wu, Jian Zhang, Zhiwei Gan   +4 more
doaj   +1 more source

Application of Mesoporous Silica Nanoparticles in Cancer Therapy and Delivery of Repurposed Anthelmintics for Cancer Therapy

Pharmaceutics, 2022
This review focuses on the biomedical application of mesoporous silica nanoparticles (MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and specifically on overcoming the challenges of currently available anthelmintics (e.
Maedeh Koohi Moftakhari Esfahani, S. Alavi, P. Cabot, N. Islam, E. Izake   +4 more
semanticscholar   +1 more source

Comparison of the efficacy of macrocyclic lactone anthelmintics, either singly or in combination with other anthelmintic(s), in nine beef herds in southern NSW.

Australian Veterinary Journal, 2023
Anthelmintic resistance (AR) is a well-recognized challenge in farmed ruminants. The use of anthelmintics in combination is one of the strategies recommended to slow the rate of AR development.
M. Allworth, B. Goonan, J. Nelson, G. Kelly, S. McGrath, R. Woodgate   +5 more
semanticscholar   +1 more source

Anthelmintic efficiency of synthetic and herbal compounds against gastrointestinal nematodes in naturally infected goats [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2020
The present study was aimed to assess the anthelmintic resistance against gastrointestinal (GI) nematode infections in goats. GI nematode infected goats (n=120) were randomly assigned to six treated groups, and untreated control group.
Saqib REHMAN, Kiran AFSHAN, Abdul RAZZAQ, Munib HUSSAIN, Sabika FIRASAT   +4 more
doaj   +1 more source

Condensed tannins act as anthelmintics by increasing the rigidity of the nematode cuticle

Scientific Reports, 2022
Tannins and tanniferous plant extracts have been discussed as sustainable means for helminth control in the past two decades in response to a dramatic increase of resistances towards standard anthelmintics.
L. Greiffer, E. Liebau, F. Herrmann, V. Spiegler   +3 more
semanticscholar   +1 more source

In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity

ACS Omega, 2021
Cancer is a leading cause of death worldwide and its incidence is unfortunately anticipated to rise in the next years. On the other hand, vascular endothelial growth factor receptor 2 (VEGFR-2) is highly expressed in tumor-associated endothelial cells ...
Ayman Abo Elmaaty, K. Darwish, A. Chrouda, Amira A. Boseila, M. Tantawy, Sameh S. Elhady, A. Shaik, Muhamad Mustafa, A. Al-karmalawy   +8 more
semanticscholar   +1 more source

Potential New Therapeutic Approaches Based on Punica granatum Fruits Compared to Synthetic Anthelmintics for the Sustainable Control of Gastrointestinal Nematodes in Sheep

Animals, 2022
Simple Summary The spread of helminths resistant to the most common classes of anthelmintic drugs in sheep and the presence of drug residues in the environment has prompted research to find sustainable alternative solutions for gastrointestinal nematodes
F. Castagna, Roberto Bava, V. Musolino, C. Piras, A. Cardamone, C. Carresi, Carmine Lupia, A. Bosco, L. Rinaldi, G. Cringoli, E. Palma, V. Musella, D. Britti   +12 more
semanticscholar   +1 more source

Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro

Molecules, 2021
Due to widespread multi-drug resistance in parasitic nematodes of livestock animals, there is an urgent need to discover new anthelmintics with distinct mechanisms of action.
Aya C. Taki, Abdul Jabbar, Thomas Kurz, Beate Lungerich, Guangxu Ma, Joseph J. Byrne, Marc Pflieger, Yodita Asfaha, Fabian Fischer, Bill C. H. Chang, Brad E. Sleebs, Robin B. Gasser   +11 more
doaj   +1 more source

Screening of Benzimidazole-Based Anthelmintics and Their Enantiomers as Repurposed Drug Candidates in Cancer Therapy

Pharmaceuticals, 2021
Repurposing of approved non-antitumor drugs represents a promising and affordable strategy that may help to increase the repertoire of effective anticancer drugs.
Rosalba Florio, S. Carradori, S. Veschi, D. Brocco, Teresa Di Genni, R. Cirilli, A. Casulli, A. Cama, L. De Lellis   +8 more
semanticscholar   +1 more source

Management of Rat Lungworm Disease (Neuroangiostrongyliasis) Using Anthelmintics: Recent Updates and Recommendations

Pathogens, 2022
While there have been legitimate concerns in the past regarding the use of anthelmintics for the management of neuroangiostrongyliasis (rat lungworm disease), recent studies demonstrate that they can be considered safe and efficacious, particularly ...
John Jacob, Argon Steel, Kathleen Howe, Susan Jarvi   +3 more
doaj   +1 more source