Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity [PDF]
, 2019 The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the appearance of drug resistant nematodes, there is a need to develop novel compounds, among which
Bouzat, Cecilia Beatriz +2 more
core +1 more source
Nematode control in suckler beef cattle over their first two grazing seasons using a targeted selective treatment approach [PDF]
, 2015 peer-reviewedBackground With concerns over the development of anthelmintic resistance in cattle nematode populations, we must re-examine our approach to nematode control in cattle.
Barrett, Damien +6 more
core +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
Advanced Science, EarlyView.In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug [PDF]
, 2013 BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Adelfio, R. +5 more
core +8 more sources
Comparison of the in vitro anthelmintic effects of Acacia nilotica and Acacia raddiana
Parasite, 2017 Gastrointestinal nematodes are a major threat to small ruminant rearing in the Sahel area, where farmers traditionally use bioactive plants to control these worms, including Acacia nilotica and Acacia raddiana.
Zabré Geneviève +10 more
doaj +1 more source
Studies on the Prevalence and Control of Parasitic Helminths in Natural Laying Hens [PDF]
, 2016 One societal trend that has been gaining much traction and popularity since the 21st century began is “organic” and/or “natural” food products. In 1999, the global market accounted for $15.2 billion dollars worth of organic food and drink, compared to ...
Weir, Brittany R
core +2 more sources
Use of Diatomaceous Earth and Copper Oxide Wire Particles to Control Gastrointestinal Nematodes in Lambs [PDF]
, 2020 Anthelmintic resistance (AR) urges alternatives to control gastrointestinal nematodes (GIN). Copper oxide wire particles (COWP) are more efficacious when used with other dewormers and little is known on efficacy of diatomaceous earth (DE) to control ...
Jones, Olivia
core +2 more sources
Activity Against Pythium insidiosum and Isolated Constituents of Cordia insignis Roots
Chemistry &Biodiversity, EarlyView.This study investigates the roots of Cordia insignis in search of novel treatments for pythiosis, caused by the oomycete Pythium insidiosum. Seven compounds are isolated, including steroids, a saponin, a coumarin, a fatty acid, and a glycoside, the latter two are reported for the first time in the genus.
Rennan Carlos de Oliveira +8 more
wiley +1 more source
Evaluation of five treatments to control intestinal parasites in sheep in Ayapango, state of Mexico [PDF]
Veterinary World, 2016 Aim: Intestinal parasites are one of the most common problems in sheep production systems. However, the strategies used to eliminate these parasites have not yielded satisfactory results.
Rafael Heredia +4 more
doaj +1 more source
Gastrointestinal nematodes of Ovis aries in Eastern Cape, South Africa and an evaluation of current anthelmintic procedures [PDF]
, 2015 Humans have known about helminth infections since ancient times. Today half of the human population is plagued by a nematode infection. Nematodes are responsible for billions of dollars in global crop damage annually and have had devastating effects on ...
Rowell, Melyssa
core +1 more source