ABSTRACT Frontline blinatumomab combined with chemotherapy has resulted in improved outcomes in both pediatric and adult patients with acute lymphoblastic leukemia and is considered the new cornerstone of acute lymphoblastic leukemia treatment. The role of asparaginase in this new landscape of acute lymphoblastic leukemia treatment was extensively ...
Daniel J. DeAngelo +15 more
wiley +1 more source
The trajectory of fatigue over time in breast cancer patients treated with chemotherapy: exploring the effect of anthracycline-based chemotherapy. [PDF]
Kastelein A +10 more
europepmc +1 more source
This study investigated the effects of clinically relevant concentrations of doxorubicin (Dox; 5 μM), commonly used in anticancer therapy, on adipose‐derived stem cells (ADSCs). Dox induced ADSC dysfunction, characterized by reduced mitochondrial activity, apoptosis, oxidative stress, premature senescence, cytoskeletal alterations, and cell cycle ...
Aleksandra Skubis‐Sikora +5 more
wiley +1 more source
New-Onset Atrial Fibrillation as an Early Marker of Anthracycline-Associated Cardiotoxicity and Mortality: A Retrospective Study. [PDF]
Homeniuk A, Karthikeyan G, Atrash A.
europepmc +1 more source
Correction for Abels et al., Manipulating anthracyclines for deeper tissue penetration and implications for glycolytic tissues. [PDF]
europepmc +1 more source
Caught in the crossfire: cardiac complications of cancer therapy. [PDF]
Guerra G +4 more
europepmc +1 more source
Antiangiogenic‐based regimens demonstrated superior efficacy compared to chemotherapy alone in heavily pretreated MBC patients, with manageable AEs. ABSTRACT Background The prognosis for metastatic breast cancer (MBC) remains poor, and treatment options are limited for patients with heavily pretreated disease. Although antiangiogenic agents may provide
Yuanyi Wang +6 more
wiley +1 more source
CT-derived myosteatosis for baseline risk stratification of cardiotoxicity in patients with diffuse large B-cell lymphoma receiving anthracyclines. [PDF]
Shen H +6 more
europepmc +1 more source
Clinical Advances in Breast Cancer: A Comprehensive Overview of Full‐Course Disease Management
This review provides a comprehensive overview of clinical advances in breast cancer, highlighting subtype‐specific therapeutic paradigms. It underscores the full‐cycle integration of innovative therapies, as well as the growing role of biomarker‐guided strategies in advancing precision medicine.
Xuenan Peng, Yujing Tan, Fei Ma
wiley +1 more source
Sodium-Glucose Cotransporter-2 Inhibitors in Anthracycline-Treated Cancer Patients: A Narrative Review of Emerging Cardioprotective Evidence. [PDF]
Nabhan E +4 more
europepmc +1 more source

