Results 1 to 10 of about 29,532 (111)

Optimising anti-seizure medication timing using a dynamic network model of seizure rhythms [PDF]

Frontiers in Network Physiology
Epileptic seizures and interictal discharges exhibit robust circadian and multidien rhythms, yet the interaction between these biological cycles and anti-seizure medication (ASM) pharmacology remains poorly understood.
Jake Ahern, Udaya Seneviratne, Udaya Seneviratne, Wendyl D’Souza, Mark J. Cook, John R. Terry, John R. Terry   +6 more
doaj   +2 more sources

The Road Not Taken: Misclassifying an Anti‐Seizure Medication as a Failure [PDF]

Annals of Clinical and Translational Neurology
Objective To quantify how often anti‐seizure medications (ASMs) appear ineffective yet provide benefit when considering seizure frequency (SF) variability. Methods We used the CHOCOLATES seizure diary simulator to generate 100,000 patient seizure diaries
Christopher N. Henry, Daniel M. Goldenholz   +1 more
doaj   +2 more sources

Sarcopenia and anti‐seizure medication response in juvenile myoclonic epilepsy [PDF]

Brain and Behavior
Introduction This study aimed to investigate the presence of sarcopenia in patients with juvenile myoclonic epilepsy (JME) and the association between sarcopenia and response to anti‐seizure medication (ASM) in patients with JME.
Jinseung Kim, Ho‐Joon Lee, Dong Ah Lee, Kang Min Park   +3 more
doaj   +2 more sources

Anti-seizure medication prescription preferences: a Moroccan multicenter study [PDF]

Frontiers in Neurology
BackgroundThe management of epilepsy is mainly based on antiseizure medications (ASMs). More than 20 ASMs have been introduced in clinical practice, providing a multitude of prescription choices. To date, there are no published data on the trends in ASMs
Yahya Naji, Yahya Naji, Wafa Hrouch, Wafa Hrouch, Sara Laadami, Sara Laadami, Nawal Adali, Nawal Adali   +7 more
doaj   +2 more sources

Anti-seizure medication treatment trials prior to pre-surgical evaluation [PDF]

Epilepsy & Behavior Reports, 2022
Purpose: Our study evaluates patterns of anti-seizure medication (ASM) usage prior to pre-surgical evaluation in drug resistant epilepsy (DRE). Methods: We conducted a retrospective study of patients with DRE presenting for pre-surgical evaluation from 1/
Vishal Pandya, Patrick Bauer, Serena Thompson, Christopher T. Anderson, Manoj Raghavan, Chad Carlson   +5 more
doaj   +2 more sources

Initial Monotherapy and Further Anti-seizure Medication Regimens in Adult Patients with Epilepsy: A Population-Based, Longitudinal, Retrospective Analysis of German Prescription Data [PDF]

Neurology and Therapy
Introduction In Germany, approximately 30% of people with epilepsy do not achieve seizure control with anti-seizure medication (ASM). ASM prescription timing and selection are crucial parameters affecting outcomes; however, the prescription ...
Adam Strzelczyk, Karel Kostev, Nils G. Margraf, Andreas Schulze-Bonhage   +3 more
doaj   +2 more sources

Drosophila melanogaster as a rapid in vivo assay system for preclinical anti‐seizure medication testing [PDF]

Epilepsia Open
Epilepsy represents a significant medical challenge, with a third of patients failing to achieve seizure freedom despite the use of multiple different anti‐seizure medications (ASM). Drug resistance is common in genetically caused epilepsies.
Emma V. Töfflinger, Konstantin L. Makridis, M.‐Marcel Heim, David Owald, Angela M. Kaindl   +4 more
doaj   +2 more sources

Seizure control by adding on other anti-seizure medication on seizure during levetiracetam administration in patients with glioma-related epilepsy [PDF]

BMC Cancer, 2023
Background Epilepsy is a major symptom in patients with glioma. Levetiracetam (LEV) is recognized as a first-line treatment for glioma-related epilepsy.
Etsuko Yamamoto Hattori, Yoshiki Arakawa, Yohei Mineharu, Keiko Furukawa, Yukinori Terada, Yukihiro Yamao, Masahiro Tanji, Takayuki Kikuchi, Susumu Miyamoto   +8 more
doaj   +2 more sources

Trends of anti-seizure medication prescribing pattern in traumatic brain injury patients for the prevention of posttraumatic seizure in Taiwan [PDF]

Epilepsy & Behavior Reports
Traumatic brain injury (TBI) patients are recommended to receive anti-seizure medication (ASM) as posttraumatic seizure (PTS) prophylaxis. However, the utilization of ASM, including the prescription patterns and associated clinical characteristics, is ...
Hsin-Tien Lee, Fen-Fen Liao, Sui-Sum Kung, Shang-Jyh Hwang, Kun-Pin Hsieh   +4 more
doaj   +2 more sources

Management of Anti-Seizure Medications during Pregnancy: Advancements in The Past Decade

Pharmaceutics, 2022
Management of seizures often involves continuous medication use throughout a patient’s life, including when a patient is pregnant. The physiological changes during pregnancy can lead to altered drug exposure to anti-seizure medications, increasing ...
Charul Avachat, Jessica M. Barry, Xintian Lyu, Catherine M. Sherwin, Angela K. Birnbaum   +4 more
doaj   +1 more source