Results 1 to 10 of about 28,601 (275)

Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures

Neuropsychiatric Disease and Treatment, 2009
Carol M Ulloa, Allen Towfigh, Joseph SafdiehDepartment of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY, USAAbstract: Levetiracetam is a second-generation antiepileptic drug (AED) with a unique chemical structure ...
Carol M Ulloa, Allen Towfigh, Joseph Safdieh   +2 more
doaj   +1 more source

A meta-analysis of randomized controlled trials on levetiracetam in the treatment of pediatric patients with epilepsy

Neuropsychiatric Disease and Treatment, 2018
Lanlan Zhang,1 Chengzhong Wang,1 Wei Li2 1Department of Pediatric Neurology, Yancheng Maternal and Child Health Hospital, 2Department of Medical Imaging, Jiangsu Vocational College of Medicine, Yancheng, China Objective: To evaluate clinical efficacy ...
Zhang LL, Wang CZ, Li W
doaj   +1 more source

Cost-effectiveness analysis of intravenous levetiracetam versus intravenous phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain injury

ClinicoEconomics and Outcomes Research, 2010
Rashid Kazerooni1, Mark Bounthavong1,21Pharmacoeconomics/Formulary Management, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA; 2UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA, USAObjective: There has been ...
Rashid Kazerooni, Mark Bounthavong
doaj   +1 more source

Correlation of elevated lamotrigine and levetiracetam serum/plasma levels with toxicity: A long-term retrospective review at an academic medical center

Toxicology Reports, 2021
Lamotrigine and levetiracetam are widely used second-generation anti-epileptic drugs. Existing literature indicates that overdose of either drug is typically benign, but neurologic and cardiac toxicity can occur in some cases. In this retrospective study,
Kelly E. Wood, Kendra L. Palmer, Matthew D. Krasowski   +2 more
doaj   +1 more source

Real-World Evidence on Levetiracetam-Induced Hypokalemia: An Active Comparator Cohort Study

Drugs - Real World Outcomes
Background Levetiracetam is an anti-seizure medication (ASM) with an established safety profile. However, a potential safety signal of hypokalemia following levetiracetam use was published in the World Health Organization newsletter.
Ohoud Almadani, Raseel Alroba, Almaha Alfakhri, Sumaya Almohareb, Turki Althunian, Adel A. Alrwisan   +5 more
doaj   +1 more source

Levetiracetam Affects Differentially Presynaptic Proteins in Rat Cerebral Cortex

Frontiers in Cellular Neuroscience, 2017
Presynaptic proteins are potential therapeutic targets for epilepsy and other neurological diseases. We tested the hypothesis that chronic treatment with the SV2A ligand levetiracetam affects the expression of other presynaptic proteins.
Daniele Marcotulli, Giorgia Fattorini, Giorgia Fattorini, Luca Bragina, Luca Bragina, Jessica Perugini, Fiorenzo Conti, Fiorenzo Conti   +7 more
doaj   +1 more source

Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum

Parkinson's Disease, 2015
L-DOPA-induced dyskinesias (LID) remain a major problem of long-term therapy of Parkinson’s disease. Levetiracetam, a new antiepileptic drug, has been shown to reduce LID, but the mechanisms underlying its effects are unknown.
Huan Du, Shuke Nie, Guiqin Chen, Kai Ma, Yan Xu, Zhentao Zhang, Stella M. Papa, Xuebing Cao   +7 more
doaj   +1 more source

Efficacy and safety of levetiracetam in preventing postoperative seizures in adult patients with brain tumors: a meta-analysis

Frontiers in Neurology
ObjectiveSeizures are one of the most common symptoms in patients with brain tumor. The efficacy of prophylactic antiepileptic agents in reducing postoperative seizures in patients with brain tumor remains disputed.
Yongyi Zhang, Haoming Li, Bin Zhang, Junchen Zhang, Chengde Li   +4 more
doaj   +1 more source

A Case of Devic’s Syndrome Presenting with Tonic Spasm: Response to Levetiracetam Treatment

Balkan Medical Journal, 2011
Neuromyelitis optica or Devic’s syndrome is a rare autoimmune disorder which is characterized by inflammatory demyelination of the optic nerves and the spinal cord.
Alev Leventoğlu, Demet Karadağ, Zülküf Mehmet Önal   +2 more
doaj  

Exploratory study on the potential benefits of prophylactic levetiracetam after acute spontaneous intracerebral hemorrhage

Frontiers in Neurology
ImportanceCurrent guidelines recommend against the routine use of seizure prophylaxis in acute spontaneous intracerebral hemorrhage (sICH).ObjectiveThe goal of this study is to evaluate if the use of prophylactic levetiracetam resulted in reduced ...
Marc A. Babi, Marc A. Babi, Marc A. Babi, Irina Lishen, Barbara Pierre Louis, Katelyn Woodbury, Anthony Kennedy, Fouad Abuzeid, Amre Nouh, Amre Nouh, Amre Nouh   +10 more
doaj   +1 more source