Results 31 to 40 of about 25,256 (244)

Levetiracetam differentially alters CD95 expression of neuronal cells and the mitochondrial membrane potential of immune and neuronal cells in vitro

Frontiers in Neurology, 2014
Epilepsy is a neurological seizure disorder that affects over 100 million people worldwide. Levetiracetam, either alone, as monotherapy, or as adjunctive treatment, is widely used to control certain types of seizures. Despite its increasing popularity as
Susannah K Rogers, Lee A Shapiro, Lee A Shapiro, Lee A Shapiro, Richard P Tobin, Benjamin eTow, Aleksej eZuzek, Sanjib eMukherjee, Sanjib eMukherjee, Sanjib eMukherjee, M. Karen eNewell-Rogers, M. Karen eNewell-Rogers   +11 more
doaj   +1 more source

Adherence to and persistence with lacosamide, perampanel, lamotrigine, and levetiracetam in adult patients with focal epilepsy in Japan: A descriptive cohort study using a claims database

Heliyon, 2023
Objective: We evaluated adherence to and 1-year persistence of two third-generation anti-seizure medications (ASMs), lacosamide and perampanel, in adult patients with focal epilepsy, compared with lamotrigine and levetiracetam.
Siming Chen, Toshiki Fukasawa, Akio Ikeda, Masato Takeuchi, Akihiro Shimotake, Satomi Yoshida, Koji Kawakami   +6 more
doaj   +1 more source

Evaluation of Hemogram Indices of Children with Epilepsy Receiving Short-Term Levetiracetam Treatment

Archives of Epilepsy, 2022
Objective:The effects of levetiracetam on hemogram parameters are comparable with other antiepileptics. This study aimed to compare the effects of levetiracetam monotherapy for at least 6 months on hemogram indices with valproic acid.Methods:Cases aged 6-
Turgay Çokyaman, Tolga Kasap
doaj   +1 more source

Levetiracetam vs. Fosphenytoin for Second-Line Treatment of Status Epilepticus: Propensity Score Matching Analysis Using a Nationwide Inpatient Database

Frontiers in Neurology, 2020
Objective: Status epilepticus is a major emergency condition. The choice of antiepileptic drugs for second-line treatment after benzodiazepine remains controversial, including levetiracetam vs. fosphenytoin.
Kensuke Nakamura, Hiroyuki Ohbe, Hiroki Matsui, Yuji Takahashi, Aiki Marushima, Yoshiaki Inoue, Kiyohide Fushimi, Hideo Yasunaga   +7 more
doaj   +1 more source

Add-on Effect of Levetiracetam on Cognitive Activity of Carbamazepine and Topiramate Treated Healthy Rats [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Many antiseizure drugs are used for non-epileptic indications like bipolar disorder, anxiety, neuropathic pain, prophylaxis of migraine, etc.
Priti Dhande, Satish Gonarkar, Dhara Sanghavi, Vijaya Pandit   +3 more
doaj   +1 more source

508 Comparing effectiveness and safety of levetiracetam loading doses among patients with status epilepticus.

Journal of Clinical and Translational Science, 2022
OBJECTIVES/GOALS: Our long-term goal is to improve the clinical outcomes of patients with status epilepticus through increasing the level of evidence surrounding guidelines.
Bertha De Los Santos, Brian J Barnes, Rose Cohen, Halinder Mangat   +3 more
doaj   +1 more source

The role of Intravenous Levetiracetam in Treatment of Seizures in Brain Tumor Patients

Frontiers in Neurology, 2013
Levetiracetam, tradename Keppra, is a new second generation antiepileptic drug that is being used increasingly in brain tumor patients. In patients suffering with brain tumors, seizures are one of the leading neurologic complications seen in more than ...
Ekokobe eFonkem, Paul eBricker, Diana eMungall, Jose eAceves, Eromata eEbwe, Wei eTang, Wei eTang, BATOOL F. KIRMANI, BATOOL F. KIRMANI, BATOOL F. KIRMANI   +9 more
doaj   +1 more source

Antiepileptic Drug of Levetiracetam Decreases Centrotemporal Spike-Associated Activation in Rolandic Epilepsy

Frontiers in Neuroscience, 2018
The objective was to study the modulation effects of levetiracetam on the fMRI activation/deactivation patterns associated with centrotemporal spikes (CTS) in Rolandic epilepsy.
Qirui Zhang, Qirui Zhang, Fang Yang, Zheng Hu, Qiang Xu, Boris C. Bernhardt, Wei Quan, Qian Li, Zhiqiang Zhang, Guangming Lu, Guangming Lu   +10 more
doaj   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source