Short-Term Neurodevelopmental Outcome in Term Neonates Treated with Phenobarbital versus Levetiracetam: A Single-Center Experience [PDF]
BACKGROUND: Phenobarbital (PB) has been traditionally used as the first-line treatment for neonatal seizures. More recently, levetiracetam (LEV) has been increasingly used as a promising newer antiepileptic medication for treatment of seizures in ...
Barbagallo, M. +7 more
core +3 more sources
The aim of this study was to investigate levetiracetam pharmacokinetics in critically ill adult intensive care patients and to identify pathophysiological factors affecting its kinetics.
Sophia-Liberty Markantonis +6 more
doaj +1 more source
Efficacy and tolerability of adjunctive brivaracetam in patients with prior antiepileptic drug exposure: A post-hoc study. [PDF]
Brivaracetam (BRV), a selective, high-affinity ligand for synaptic vesicle protein 2A, is a new antiepileptic drug (AED) for adjunctive treatment of focal (partial-onset) seizures in adults with epilepsy.
Asadi-Pooya, Ali A. +7 more
core +2 more sources
The 4-Aminopyridine Model of Acute Seizures in vitro Elucidates Efficacy of New Antiepileptic Drugs [PDF]
Up to date, preclinical screening for new antiepileptic substances is performed by a combination of different in vivo models of acute seizures, for which large numbers of animals are necessary.
Dag, Ramazan +4 more
core +1 more source
Levetiracetam-induced rage and suicidality: Two case reports and review of literature
Background: Levetiracetam-induced rage is a rare neurobehavioral adverse effect of levetiracetam that is characterized by seething rage, uncontrollable anger, fits of fury, depression, violence, and suicidal tendencies.
Orakwue A. Molokwu +2 more
doaj +1 more source
Multiple acquired portosystemic shunts in a cat secondary to chronic diaphragmatic rupture [PDF]
A cat with a chronic diaphragmatic rupture presented with neurological signs, including twitching and focal seizures. Blood ammonia level was markedly elevated and therefore neurological signs were thought to be related to hepatic encephalopathy ...
Birchard SJ +3 more
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Limited information is available on the long-term follow-up and seizure recurrence in dogs with reactive seizures due to suspected exogenous toxicity.
Fabio Stabile, Luisa De Risio
doaj +1 more source
Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. [PDF]
BACKGROUND: Prior studies have shown that switching patients from inducing antiepileptic drugs (AEDs) to lamotrigine, levetiracetam, or topiramate reduces serum lipids and C-reactive protein (CRP). These studies were all of short duration, and some drugs,
Chervoneva, Inna +6 more
core +2 more sources
Effects of Levetıracetam Treatment on the Autonomic Nervous System Functions in Epilepsy Patients
Objectives:Sudden unexpected death in epilepsy patients is considered to be the most significant epilepsy-related cause of death, and this is associated especially with uncontrolled generalized tonic-clonic seizures, cardiac arrhythmia, decreased heart ...
Dilek YILMAZ, Burhanettin ÇİĞDEM
doaj +1 more source
Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]
IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve +4 more
core +1 more source

