Results 21 to 30 of about 29,631 (210)

Efficacy of levetiracetam for neonatal seizures in preterm infants

BMC Pediatrics, 2018
Background Neonatal seizures remain a significant clinical problem, and therapeutic options are still not diverse with limited efficacy. Levetiracetam (LEV) is a relatively new and wide spectrum anti-seizure medication with favorable pharmacokinetics and
Ji Yoon Han, Chung Joon Moon, Young Ah Youn, In Kyung Sung, In Goo Lee   +4 more
doaj   +1 more source

Adherence to anti-seizure medications and associated factors among children with epilepsy at tertiary Hospital in Southwest Ethiopia: a cross-sectional study

BMC Neurology, 2022
Background Childhood epilepsy causes a tremendous burden for the child, the family, society as well as the healthcare system. Adherence to anti-seizure medications (ASMs) is a key to treatment success.
Hawi Mohammed, Kemal Lemnuro, Teferi Mekonnen, Tsegaye Melaku   +3 more
doaj   +1 more source

Efficacy and Tolerability of Perampanel as Adjunctive Therapy in Chinese Patients With Focal-Onset Seizures: An Observational, Prospective Study

Frontiers in Neurology, 2021
Purpose: To evaluate the efficacy and tolerability of adjunctive perampanel (PER) in Chinese patients with focal-onset seizures, with or without secondarily generalized tonic-clonic seizures.Methods: Fifty-six patients aged 14–72 years were recruited ...
Ranran Zhang, Shan Qiao, Xiqin Fang, Kemo Wang, Yanting Shi, Qianwen Du, Tingting Yang, Xuewu Liu, Xuewu Liu   +8 more
doaj   +1 more source

A systematic review and meta-analysis of anti-epileptic medication non-adherence among people with epilepsy in Ethiopia

Archives of Public Health, 2020
Background Epilepsy is the common neurological disorder in the world, affecting approximately 50 million people. Anti-epileptic medication non-adherence can be a reason for long term hospitalization, repeated emergency seizure attacks, increased health ...
Zelalem Belayneh, Birhanie Mekuriaw
doaj   +1 more source

PRRT2‐positive self‐limited infantile epilepsy: Initial seizure characteristics and response to sodium channel blockers

Epilepsia Open, 2023
Objective Self‐limited infantile epilepsy (SeLIE) has distinctive clinical features, and the PRRT2 gene is known to be a considerable genetic cause.
Jiwon Lee, Young Ok Kim, Byung Chan Lim, Jeehun Lee   +3 more
doaj   +1 more source

Effect of add‐on melatonin on seizure outcomes and quality of sleep in epilepsy with idiopathic generalized tonic‐clonic seizures alone in adult patients: Cross‐sectional, randomized, double‐blind, placebo‐controlled clinical trial

Brain and Behavior, 2023
Background Effective treatment of epilepsy is a major challenge in the field of neurology. Studies have suggested that melatonin can work in epilepsy with a good safety profile.
Mehdi Maghbooli, Somayeh Alyan NajafAbadi, Ghazal MalekMahmoudi, Mohammad Hadi Molseghi   +3 more
doaj   +1 more source

Direct and indirect costs and cost-driving factors of Tuberous sclerosis complex in children, adolescents, and caregivers: a multicenter cohort study

Orphanet Journal of Rare Diseases, 2021
Background Tuberous sclerosis complex (TSC), a multisystem genetic disorder, affects many organs and systems, characterized by benign growths. This German multicenter study estimated the disease-specific costs and cost-driving factors associated with ...
Janina Grau, Johann Philipp Zöllner, Susanne Schubert-Bast, Gerhard Kurlemann, Christoph Hertzberg, Adelheid Wiemer-Kruel, Thomas Bast, Astrid Bertsche, Ulrich Bettendorf, Barbara Fiedler, Andreas Hahn, Hans Hartmann, Frauke Hornemann, Ilka Immisch, Julia Jacobs, Matthias Kieslich, Karl Martin Klein, Kerstin A. Klotz, Gerhard Kluger, Markus Knuf, Thomas Mayer, Klaus Marquard, Sascha Meyer, Hiltrud Muhle, Karen Müller-Schlüter, Anna H. Noda, Susanne Ruf, Matthias Sauter, Jan-Ulrich Schlump, Steffen Syrbe, Charlotte Thiels, Regina Trollmann, Bernd Wilken, Laurent M. Willems, Felix Rosenow, Adam Strzelczyk   +35 more
doaj   +1 more source

Systemic inflammation as a biomarker of seizure propensity and a target for treatment to reduce seizure propensity

Epilepsia Open, 2023
People with diabetes can wear a device that measures blood glucose and delivers just the amount of insulin needed to return the glucose level to within bounds.
Coral Stredny, Alexander Rotenberg, Alan Leviton, Tobias Loddenkemper   +3 more
doaj   +1 more source

Real-World Experience Treating Pediatric Epilepsy Patients With Cenobamate

Frontiers in Neurology, 2022
IntroductionIn one third of all patients with epilepsy, seizure freedom is not achieved through anti-seizure medication (ASM). These patients have an increased risk of earlier death, poorer cognitive development, and reduced quality of life.
Konstantin L. Makridis, Konstantin L. Makridis, Konstantin L. Makridis, Konstantin L. Makridis, Thomas Bast, Christine Prager, Christine Prager, Christine Prager, Tatjana Kovacevic-Preradovic, Petra Bittigau, Petra Bittigau, Petra Bittigau, Thomas Mayer, Eva Breuer, Angela M. Kaindl, Angela M. Kaindl, Angela M. Kaindl, Angela M. Kaindl   +17 more
doaj   +1 more source

A multicenter retrospective study of patients treated in the thalamus with responsive neurostimulation

Frontiers in Neurology, 2023
IntroductionFor drug resistant epilepsy patients who are either not candidates for resective surgery or have already failed resective surgery, neuromodulation is a promising option.
Madeline C. Fields, Onome Eka, Cristina Schreckinger, Patricia Dugan, Wael F. Asaad, Andrew S. Blum, Katie Bullinger, Jon T. Willie, David E. Burdette, Christopher Anderson, Imran H. Quraishi, Jason Gerrard, Anuradha Singh, Kyusang Lee, Ji Yeoun Yoo, Saadi Ghatan, Fedor Panov, Lara V. Marcuse   +17 more
doaj   +1 more source