Results 121 to 130 of about 2,808 (150)

A xanthone O-glucoside isolated from Iris setosa Pall. ex Link exhibits promising anti-amoebic activity against the brain-eating amoeba Naegleria fowleri

Phytomedicine
Primary amoebic meningoencephalitis (PAM), caused by Naegleria fowleri, poses a significant challenge in humans owing to its high mortality rate, exceeding 97 %. Current therapeutics have been unable to deliver satisfactory treatment outcomes, due to suboptimal efficacy and toxicity, highlighting the critical need for efficacious drug development.
Byoung-Kuk Na, Buyng Su Hwang, Yong Tae Jeong   +2 more
exaly   +3 more sources

Rapid in vitro test for determination of anti-amoebic activity

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1996
A rapid microplate assay for the detection of potential compounds active against Entamoeba histolytica is described. The assay is based on the metabolic reduction of a tetrazolium salt by E. histolytica trophozoites as an indicator of their viability which may be measured photometrically.
R M, Mukhopadhyay, S K, Chaudhuri
openaire   +2 more sources

Evaluation of Anti-amoebic Activity of Spring Leaf Extract of Artemisia Aucheri on Acanthamoeba (T4 strain) In vitro

Anti-Infective Agents, 2021
Background: Acanthamoeba belongs to the free-living amoebae genus that causes a widespread infection with different severities in humans and animals. Treatment of these opportunistic protozoan infections is still not safe or effective. The aim of the present study was to evaluate the effect of spring extract of Artemisia aucheri on Acanthamoeba in ...
Amir KarimiPourSaryazdi, Yeganeh KarimiPourSaryazdi, Fatemeh Ghaffarifar, Maryam Ahmadi, Leila Zaki   +4 more
openaire   +1 more source

The anti-amoebic activity of some medicinal plants used by AIDS patients in southern Thailand

Parasitology Research, 2006
The anti-amoebic activities of chloroform, methanol and water extracts from 12 Thai medicinal plants (39 extracts) commonly used by AIDS patients in southern Thailand were screened, at a concentration of 1,000 microg/ml, against Entamoeba histolytica strain HTH-56:MUTM and strain HM1:IMSS growing in vitro.
Nongyao, Sawangjaroen, S, Phongpaichit, S, Subhadhirasakul, M, Visutthi, N, Srisuwan, N, Thammapalerd   +5 more
openaire   +2 more sources

Comparative study of potent anti-amoebic and anti-inflammatory activities of different extracts from Sida rhombifolia (L)

Investigational Medicinal Chemistry and Pharmacology, 2023
Background: Sida rhombifolia (L) is a medicinal plant from tropical regions belonging to the Malvaceae family and the plantea kingdom. It is known for its multiple pharmacological properties. The aim of this work was to evaluate the anti-amoebic, and anti-inflammatory potential of Sida rhombifolia aqueous and ethanolic leaf and stem extracts harvested ...
Nsangou, Sylvain Pechangou, Ndam, Roukayatou Ndiandoukoue, Njoya, Emmanuel Mfotie, Enang II, Brice E., Njayou, Frederic N., Moundipa, Paul Fewou   +5 more
openaire   +2 more sources

ChemInform Abstract: ANTI‐AMOEBIC AND ANTITRICHOMONAL ACTIVITIES OF SOME NEW FURAN HALOACETAMIDES

Chemischer Informationsdienst, 1980
AbstractÜber die entsprechenden Furfurylamine (durch LiAlH4‐Reduktion der Furfurylidenamine bzw., im Falle einer S‐Methyl‐ oder 5‐Methoxymethy1‐Substitution, durch Mannich‐Reaktionen der betreffenden Furane mit Formaldehyd und den entsprechenden Aminen in 40‐60 proz. Ausb.
D. R. SHRIDHAR, P. G. REDDY, S. R. MOORTY, O. P. MADAN, M. JOGIBHUKTA, C. JANAKIRAM, K. K. BHOPALE, K. TRIPATHI, G. P. DATTA, S. R. DAS   +9 more
openaire   +1 more source

Anti-amoebic activity of a cecropin-melittin hybrid peptide (CM11) against trophozoites of Entamoeba histolytica

Wiener klinische Wochenschrift, 2019
Entamoeba histolytica is an intestinal parasite that is located in the lumen of the human intestine and can attack the epithelium. Antimicrobial peptides (AMPs) are effective against the wide range of microorganisms, such as bacteria, fungi, viruses, yeasts, and protozoa.
Fatemeh Mahdavi Abhari, Majid Pirestani, Abdolhossein Dalimi   +2 more
openaire   +2 more sources

Synthesis and Anti-Amoebic Activity of Gold(I), Ruthenium(II), and Copper(II) Complexes of Metronidazole

Chemistry & Biodiversity, 2005
A series of Au, Ru, and Cu complexes of metronidazole (= [1-(2-hydroxyethyl)-2-methyl-5-nitro-1H-imidazole; 1) were prepared as highly potent anti-amoebic drugs. The complexes [Au(PPh3)(1)]PF6 (2), [Ru(1)2(Cl)2(H2O)2] (3), and [Cu(1)2(mu-Cl)(H2O)]2Cl2 (4) were readily synthesized from [Au(PPh3)Cl], RuCl3 x 3 H2O, and CuCl2 x 2 H2O, respectively.
Athar, Fareeda, Husain, Kakul, Abid, Mohammad, Agarwal, Subhash M., Coles, Simon J., Hursthouse, Michael B., Maurya, Mannar R., Azam, Amir   +7 more
openaire   +2 more sources

Synthesis, Characterization, and Anti‐Amoebic Activity of N‐(Pyrimidin‐2‐yl)benzenesulfonamide Derivatives

Chemistry & Biodiversity, 2013
AbstractA new series of N‐(pyrimidin‐2‐yl)benzenesulfonamide derivatives, 3a–3i and 4a–4i, was synthesized from pyrimidin‐2‐amines, 2a–2i, with the aim to explore their effects on in vitro growth of Entamoeba histolytica. The chemical structures of the compounds were elucidated by elemental analysis, FT‐IR, 1H‐ and 13C‐NMR, and ESI mass‐spectral data ...
Abdul, Roouf Bhat, Mohammad, Arshad, Eun, Ju Lee, Smritee, Pokharel, Inho, Choi, Fareeda, Athar   +5 more
openaire   +2 more sources

Synthesis, Anti-Inflammatory, Analgaesic and Anti-Amoebic Activity Evaluation of Some Pyrimidobenzimidazole and Pyrimidopyridoimidazole Derivatives

Australian Journal of Chemistry, 2001
o -Phenylenediamine, 4-nitro-1,2-phenylenediamine, 3,4-diaminobenzophenone, 3,4-diaminotoluene, 4,5-dimethylphenylenediamine and 3,4-diaminobenzoic acid (1a–f) react with 4-isothiocyanatobutan-2-one to give the pyrimidobenzimidazole derivatives (2a–f) respectively.
Sham M. Sondhi, Monika Johar, Rakesh Shukla, Ram Raghubir, Neelam Bharti, Amir Azam   +5 more
openaire   +1 more source