Results 21 to 30 of about 528,186 (197)

Preparation and evaluation of compressed coated tablets using polyelectrolyte complex for targeted delivery of anti-amoebic drug

open access: yesBulletin of Pharmaceutical Sciences. Assiut, 2022
An unwanted absorption of anti-amoebic drug at upper gastrointestinal tract (GIT) causes numerous side effects and requires higher doses to get therapeutic effect.
H. Badwaik   +5 more
semanticscholar   +1 more source

High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds

open access: yesbioRxiv, 2021
Entamoeba histolytica is a disease-causing parasitic amoeba which affects an estimated 50 million people worldwide, particularly in socioeconomically vulnerable populations experiencing water sanitation issues. Infection with E.
Conall Sauvey   +4 more
semanticscholar   +1 more source

Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillaris

open access: yesAntibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are pathogenic free-living amoebae that infect the central nervous system with over 95% mortality rates.
Ruqaiyyah Siddiqui   +6 more
doaj   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Antiamoebic Properties of Ceftriaxone and Zinc-Oxide–Cyclodextrin-Conjugated Ceftriaxone

open access: yesAntibiotics, 2022
Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent.
Zinb Makhlouf   +6 more
doaj   +1 more source

Lead optimisation of dehydroemetine for repositioned use in malaria [PDF]

open access: yes, 2020
Drug repositioning offers an effective alternative to de novo drug design to tackle the urgent need for novel anti-malarial treatments. The anti-amoebic compound, emetine dihydrochloride, has been identified as a potent in-vitro inhibitor of the multi ...
Abubaker, M   +8 more
core   +3 more sources

Piperine Alkaloid Induces Anti-Cancer Effects in Human Breast Carcinoma Cells by Targeting Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway

open access: yesIndian Journal of Pharmaceutical Sciences, 2022
Piperine is a dietary alkaloid with huge pharmacological importance and was first isolated from pepper extract. It has been reported with anti-cancer, anti-amoebic, anti-mycobacterial, anti-mutagenic, anti-convulsant, anti-asthmatic, immunomodulatory ...
Jun Zhang, Zhetong Liang, Zhouhai Zhang
semanticscholar   +1 more source

Identification of Naegleria fowleri proteins linked to primary amoebic meningoencephalitis [PDF]

open access: yes, 2017
Naegleria fowleri (N. fowleri) causes primary amoebic meningoencephalitis, a rapidly fatal disease of the central nervous system. N. fowleri can exist in cyst, flagellate or amoebic forms, depending on environmental conditions.
Cabral, Guy A   +4 more
core   +2 more sources

Antiamoebic Properties of the Actinomycete Metabolites Echinomycin A and Tirandamycin A [PDF]

open access: yes, 2012
Entamoeba histolytica infects 50 million people per year, causing 100,000 deaths worldwide. The primary treatment for amoebiasis is metronidazole. However, increased pathogen resistance combined with the drug’s toxic side effects encourages a search for ...
Espinosa, Avelina   +3 more
core   +3 more sources

Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells [PDF]

open access: yes, 2004
The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Alsam   +32 more
core   +1 more source

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