Results 101 to 110 of about 163,561 (303)

Effect of isopregnanolone on rapid tolerance to the anxiolytic effect of ethanol

Brazilian Journal of Psychiatry, 2006
OBJETIVE: It has been shown that neurosteroids can either block or stimulate the development of chronic and rapid tolerance to the incoordination and hypothermia caused by ethanol consumption. The aim of the present study was to investigate the influence
Debatin Thaize, Barbosa Adriana Dias Elpo   +1 more
doaj  

Psychosocial characteristics of the general population who habitually use hypnotics: Results from a national survey on drug use among the Japanese

PCN Reports
Aim The aim of this study was to examine the characteristics of habitual hypnotic users in Japan. Methods This nationwide, cross‐sectional survey used self‐administered questionnaires.
Satomi Mizuno, Takuya Shimane, Satoshi Inoura, Toshihiko Matsumoto   +3 more
doaj   +1 more source

Chronic use of diazepam in primary healthcare centers: user profile and usage pattern

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Chronic use of benzodiazepines is frequent in general practice. The aim of this study was to describe the usage pattern and profile of chronic users of diazepam who had been consuming this drug for a minimum of thirty-six months ...
Carmen Sylvia Ribeiro, Renata Cruz Soares Azevedo, Viviane Franco da Silva, Neury José Botega   +3 more
doaj   +1 more source

Interpreting algorithmic information cues: User sensemaking of search autocomplete moderation

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Autocomplete is a search feature that algorithmically generates information cues for any keywords entered in the search bar. While this feature makes the search process more efficient, it also frequently produces biased, misleading, offensive, or otherwise inappropriate suggestions.
Shagun Jhaver
wiley   +1 more source

Marketed nonsteroidal anti-inflammatory agents, antihypertensives, and human immunodeficiency virus protease inhibitors: as-yet-unused weapons of the oncologists’ arsenal

, 2015
Panagiota Papanagnou,1 Panagiotis Baltopoulos,2 Maria Tsironi1 1Department of Nursing, Faculty of Human Movement and Quality of Life Sciences, University of Peloponnese, Sparta, 2Department of Sports Medicine and Biology of Physical Activity ...
Baltopoulos P, Papanagnou P, Tsironi M
core  

Anti-Tumor Mechanisms of Novel 3-(4-Substituted Benzyl)-5-Isopropil-5- Phenylhydantoin Derivatives in Human Colon Cancer Cell Line

, 2019
Background: Hydantoin and its newly synthesized derivatives have recently become a focus of interest due to their numerous biological activities and newly emerging beneficial effects in different pathological conditions, including cancer.
Matić, Miloš, Ušćumlić, Gordana, Obradović, Ana, Božić, Bojan, Vuković, Nenad, Ognjanović, Branka, Vukić, Milena, Božić Nedeljković, Biljana, Djurdjevic, Predrag   +8 more
core   +1 more source

Effect of benzodiazepines on thyroglobulin, anti-thyroglobulin, anti-thyroid peroxidase, and thyroid stimulating hormone in rat

Medical Journal of Dr. D.Y. Patil University, 2014
Background: Benzodiazepines are widely used as psychoactive agents and the side effects of benzodiazepines to the endocrine system are reported. Objective: This study was designed to explore the effects of the benzodiazepines - lorazepam and clonazepam -
Mohammad-Hasan Khadem-Ansari, Ali Ahani, Peyman Mikaeili, Yousef Rasmi   +3 more
doaj   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Experimental studies of the interaction between people and virtual humans with a focus on social anxiety

, 2010
Psychotherapy has been one of the major applications of Virtual Reality technology; examples include fear of flying, heights, spiders, and post‐traumatic stress disorder.
Pan, X.
core  

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source