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Chapter 2: Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
Publisher Summary This chapter includes report of some novel structures of different compounds and its derivatives and analogs that continue to dominate the pharmacologically related areas of anti-anxiety, anticonvulsant, and sedative-hypnotic therapy.
Marvin Cohen
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AbstractDiazepam is one of the most widely used, broad‐spectrum anti‐anxiety agents. The aim of this study was to evaluate the efficacy of diazepam, and to establish whether it is more effective than a placebo in improving the various neurotic anxiety states seen in patients with neurosis or psychosomatic disease.
Ataru Inagaki +3 more
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NALOXONE POTENTIATES THE EFFECTS OF SUB-EFFECTIVE DOSES OF ANTI-ANXIETY AGENTS IN RATS AND MICE
Serge Barreau +2 more
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Avicenna Journal of Phytomedicine, 2017
Objectives: The extract of Lippia citriodora and its main component, verbascoside, are known for their hypnotic effects in traditional medicine. In this study, the anxiolytic and hypnotic effects of L.
B. Razavi, N. Zargarani, H. Hosseinzadeh
semanticscholar +1 more source
Objectives: The extract of Lippia citriodora and its main component, verbascoside, are known for their hypnotic effects in traditional medicine. In this study, the anxiolytic and hypnotic effects of L.
B. Razavi, N. Zargarani, H. Hosseinzadeh
semanticscholar +1 more source
Psychedelics as anti-inflammatory agents
International Review of Psychiatry, 2018Serotonin (5-hydroxytryptamine, 5-HT)2A receptor agonists have recently emerged as promising new treatment options for a variety of disorders. The recent success of these agonists, also known as psychedelics, like psilocybin for the treatment of anxiety,
Thomas W. Flanagan, C. Nichols
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Journal of Ethnopharmacology, 2023
Among the fewest drugs discovered are those belonging to the class of anxiolytics. Although some drug targets for anxiety disorders are established, it is hard to modify and selectively choose the active principle for those targets. Thus, the ethnomedical approach to treating anxiety disorders remains one of the most prevalent ways for (self)managing ...
Nikola M. Stojanović +3 more
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Among the fewest drugs discovered are those belonging to the class of anxiolytics. Although some drug targets for anxiety disorders are established, it is hard to modify and selectively choose the active principle for those targets. Thus, the ethnomedical approach to treating anxiety disorders remains one of the most prevalent ways for (self)managing ...
Nikola M. Stojanović +3 more
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Enhancement of 3H-diazepam binding by SQ 65,396: A novel anti-anxiety agent
Pharmacology Biochemistry and Behavior, 1978SQ 65,396, a clinically active anti-anxiety agent, enhanced the binding of 3H-diazepam at 1.5 nM. This effect was due to an increase in the affinity for the ligand, without a change in the number of 3H-diazepam binding sites. This action of SQ 65,396 may mediate its anti-anxiety effects by affecting the action of an endogenous modulator of the ...
Claire A. Klepner +3 more
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