Results 211 to 220 of about 60,411 (263)
Chapter 2. Anti-Anxiety Agents, Anticonvulsants and Sedative-Hypnotics
, 1977 Publisher Summary This chapter describes the metabolic studies of Lorazepam in man and animals, Pinazepams in man, Diazepam in human kidney cortex microsomes and bile, and Nitrazepam in rabbit urine. N-desmethyldiazepam is a new human metabolite of chlorodiazepoxid, e.g Diazepam and its main active metabolite desmethyldiazepam, pass into the breast ...
Gregory B. Bennett, William J. Houlihan
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Chapter 3 Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
, 1979 Publisher Summary This chapter summarizes the nature of the benzodiazepine receptor that has been characterized further, by the demonstration that a single class of binding sites exists in rat brain for a structurally diverse series of benzodiazepines.
Joel G. Berger, Louis C. Iorio
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Spiro Benzodiazepine Substituted Fluorocoumarins as Potent Anti-Anxiety Agents
Russian Journal of Bioorganic Chemistry, 2021 1,5-Benzodiazepines are one of the important class of tranquilizers. The fusion of heterocyclic systems like coumarins and indolines with the benzodiazepine seems quite encouraging for the synthesis of derivatives with enhanced anti-anxiety property. The benzodiazepine derivatives containing fluorine were synthesized and studied for their anti-anxiety ...
Dayanand Patagar +8 more
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Chapter I. Antipsychotic and Anti-anxiety Agents
, 1968 Publisher Summary This chapter elaborates on antipsychotic and antianxiety agents. The reported contribution of pyrrole nuclei to the sedative action of ketone derivatives encouraged the synthesis of relatives of ketone derivatives in which the benzene ring was replaced by pyrrole.
Irwin J Pachter, Alan A. Rubin
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Anti-anxiety agents: duration of use and characteristics of users in the U.S.A.
Current Medical Research and Opinion, 1984 A national survey of psychotherapeutic drug use was carried out in the U.S.A. in 1979. Data were obtained from a probability sample (n = 3161) of adults in the general population, using a clinically-oriented interview lasting an average of 90 minutes.
Eberhard H. Uhlenhuth +2 more
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Chapter 2. Anti-Anxiety Agents, Anticonvulsants & Sedative-Hypnotics
, 1983 Publisher Summary Studies on pharmacotherapy for anxiety continue to evolve along the dual paths of agents and actions. While benzodiazepines (BZs) continue to be the agents of choice for anxiolysis, new series of non-BZ compounds are emerging that may offer alternatives in the management of anxiety disorders.
J. S. New +2 more
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A simple and reliable conflict procedure for testing anti-anxiety agents
Psychopharmacologia, 1971 The effects of three benzodiazepines (chlordiazepoxide, diazepam, and oxazepam), meprobamate, pentobarbital, d-amphetamine sulfate, magnesium pemoline, and scopolamine hydrobromide were studied with a simple conflict procedure in which thirsty naive rats were periodically administered shocks for licking water.
Bernard Beer +2 more
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Chapter 1. Antipsychotic and Anti-anxiety Agents
, 1969 Publisher Summary This chapter discusses results of studies focusing on antipsychotic and antianxiety agents. Studies revealed that medazepam alleviates anxiety and tension in children and adults with minimal sedative side effect and without impairment of working capacity or normal alertness.
Irwin J Pachter, Alan A. Rubin
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Chapter 32 Hypnotics and anti-anxiety agents
, 1997 Summary Depression of the central nervous system can be achieved with a wide variety of chemical agents. Depending on dose, increasing levels of effect consisting of (a) anti-anxiety effects, (b) sedation, (c) sleep, (d) anesthesia, and (e) coma (with risk of a fatal outcome) may be produced. Frequently the same agent may be used at a greater dose to
Arthur Raines
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Chapter 1. Antipsychotic and Antianxiety Agents
, 1972 Publisher Summary This chapter presents results of studies that analyze antipsychotic and antianxiety agents. The use of long-acting fluphenazine in the management of schizophrenia and its comparison with conventional therapy was reviewed. Studies of other 6-6-6 tricyclics included several new phenothiaaine derivatives. A diazabicyclononane analog of
Charles L. Zirkle, Carl Kaiser
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