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Animal models for the study of anti-anxiety agents: A review
Neuroscience & Biobehavioral Reviews, 1985Animal models for the study of anxiolytic agents are reviewed and evaluated according to pharmacological and behavioral criteria. Although there are important exceptions, in general, most early animal models have not provided a reliable basis for identifying compounds with potential anxiolytic action, or for delineating the mechanisms of anxiolytic ...
D. Treit
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Chapter 3 Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
, 1979 Publisher Summary This chapter summarizes the nature of the benzodiazepine receptor that has been characterized further, by the demonstration that a single class of binding sites exists in rat brain for a structurally diverse series of benzodiazepines.
Joel G. Berger, Louis C. Iorio
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Chapter 1. Antipsychotic and Anti-anxiety Agents
1969Publisher Summary This chapter discusses results of studies focusing on antipsychotic and antianxiety agents. Studies revealed that medazepam alleviates anxiety and tension in children and adults with minimal sedative side effect and without impairment of working capacity or normal alertness.
Irwin J. Pachter, Alan A. Rubin
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Anti-anxiety agents: duration of use and characteristics of users in the U.S.A.
Current Medical Research and Opinion, 1984A national survey of psychotherapeutic drug use was carried out in the U.S.A. in 1979. Data were obtained from a probability sample (n = 3161) of adults in the general population, using a clinically-oriented interview lasting an average of 90 minutes.
G D, Mellinger +2 more
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Chapter 2. Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
, 1982 Publisher Summary This chapter discusses the biochemical mechanisms of action of anxiolytics, anticonvulsants and sedatives, and to a better understanding of the causes and nature of the disorders for which they are used. Strong evidence continues to support a functional link between benzodiazepines (BZ), gamma-aminobutyric acid (GABA), and chloride ...
RichardC. Effland
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Sedatives and anti-anxiety agents in critical illness
, 2016 Abstract Sedative and anti-anxiety agents are administered to many mechanically-ventilated intensive care unit (ICU) patients. While commonly considered supportive care, suboptimal administration of sedatives has been linked to longer duration of mechanical ventilation and longer ICU length of stay.
Curtis N. Sessler, Katie M. Muzevich
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Chapter 2. Anti-Anxiety Agents, Anticonvulsants & Sedative-Hypnotics
, 1983 Publisher Summary Studies on pharmacotherapy for anxiety continue to evolve along the dual paths of agents and actions. While benzodiazepines (BZs) continue to be the agents of choice for anxiolysis, new series of non-BZ compounds are emerging that may offer alternatives in the management of anxiety disorders.
Joseph P. Yevich +2 more
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Ondansetron: A Novel Anti-anxiety Agent
, 1991 Although the widely used benzodiazepines for control of anxiety have met with high patient acceptance, there is a hesitation about long-term use owing to the possibility of dependence. The new azaspirodecanedione compounds such as buspirone (Buspar) are free from dependence but raise the spectre of tardive dyskinesia since they are derivatives of the ...
F.S. Abuzzahab
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