Results 231 to 240 of about 60,411 (263)
Some of the next articles are maybe not open access.
Journal of Ethnopharmacology, 2023
Among the fewest drugs discovered are those belonging to the class of anxiolytics. Although some drug targets for anxiety disorders are established, it is hard to modify and selectively choose the active principle for those targets. Thus, the ethnomedical approach to treating anxiety disorders remains one of the most prevalent ways for (self)managing ...
Nikola M. Stojanović +3 more
openaire +2 more sources
Among the fewest drugs discovered are those belonging to the class of anxiolytics. Although some drug targets for anxiety disorders are established, it is hard to modify and selectively choose the active principle for those targets. Thus, the ethnomedical approach to treating anxiety disorders remains one of the most prevalent ways for (self)managing ...
Nikola M. Stojanović +3 more
openaire +2 more sources
Behavioural Validation of a Light/Dark Choice Procedure for Testing Anti-Anxiety Agents
Behavioural Processes, 1989In order to teat the behavioural value of a two-chambered light/dark choice procedure used for pharmacological studies, we investigated the effects of several internal and external factors on two variables: the time spent by mice in the lit box (TLB) and the number of transitions between the lit box and the dark one.
Catherine Belzung +2 more
openaire +3 more sources
Sedatives and anti-anxiety agents in critical illness
2016Sedative and anti-anxiety agents are administered to many mechanically-ventilated intensive care unit (ICU) patients. While commonly considered supportive care, suboptimal administration of sedatives has been linked to longer duration of mechanical ventilation and longer ICU length of stay.
Curtis N. Sessler, Katie M. Muzevich
openaire +1 more source
Enhancement of 3H-diazepam binding by SQ 65,396: A novel anti-anxiety agent
Pharmacology Biochemistry and Behavior, 1978SQ 65,396, a clinically active anti-anxiety agent, enhanced the binding of 3H-diazepam at 1.5 nM. This effect was due to an increase in the affinity for the ligand, without a change in the number of 3H-diazepam binding sites. This action of SQ 65,396 may mediate its anti-anxiety effects by affecting the action of an endogenous modulator of the ...
Claire A. Klepner +3 more
openaire +3 more sources
Ondansetron: A Novel Anti-anxiety Agent
1991Although the widely used benzodiazepines for control of anxiety have met with high patient acceptance, there is a hesitation about long-term use owing to the possibility of dependence. The new azaspirodecanedione compounds such as buspirone (Buspar) are free from dependence but raise the spectre of tardive dyskinesia since they are derivatives of the ...
openaire +2 more sources
Chapter 3. Anti-Anxiety Agents, Anticonvulsants and Sedative-Hypnotics
1978Publisher Summary A specific benzodiazepine receptor has been found in rat and human brain cells that might mediate their pharmacological activities. Binding sites in the rat are unevenly distributed throughout the brain, and a loose parallel between the pharmacological potency and receptor affinity is found.
Gregory B. Bennett, William J. Houlihan
openaire +2 more sources
Chapter 4. Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
1981Publisher Summary Rapid advances have been made in understanding the neurochemical mechanisms of benzodiazepines (BZs) and similar compounds responsible for their therapeutic actions. The “GABA hypothesis” relating to the actions of BZs in the brain continues to gain support.
Richard C. Effland, Manfred F. Försch
openaire +2 more sources
Chemotherapy in dental practice. Anti-anxiety agents. I. Meprobromate.
Dental digest, 1969 Ben Gurney
openaire +2 more sources
[Anti-emetic and anti-anxiety agents].
Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec, 2010 Jérôme Ouellet
openaire +2 more sources
Chapter 2. Anti-Anxiety Agents, Anticonvulsants, and Sedative-Hypnotics
1982Publisher Summary This chapter discusses the biochemical mechanisms of action of anxiolytics, anticonvulsants and sedatives, and to a better understanding of the causes and nature of the disorders for which they are used. Strong evidence continues to support a functional link between benzodiazepines (BZ), gamma-aminobutyric acid (GABA), and chloride ...
openaire +2 more sources