Results 71 to 80 of about 4,075,451 (292)

Thymulin: An emerging anti-inflammatory molecule

open access: yes, 2005
Thymulin is a neuroendocrine hormone with immunoregulatory actions. Originally known as 'serum thymic factor' (FTS), thymulin binds to a carrier protein and zinc (Zn2+) to exert its biologic properties.
Haddad J.J.   +2 more
core   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren   +11 more
wiley   +1 more source

An update on the pharmacological treatment of anxiety and related disorders

open access: yesSouth African Family Practice, 2016
The anxiety disorders, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD) are common and debilitating, often coexist with medical and psychiatric conditions, and usually require long-term treatment.
K. Outhoff
doaj   +1 more source

Anti-vascular endothelial growth factor in neovascular age-related macular degeneration – a systematic review of the impact of anti-VEGF on patient outcomes and healthcare systems

open access: yesBMC Ophthalmology, 2020
Background Systematically review the evidence describing the impact of anti–vascular endothelial growth factor (anti-VEGF) therapy on neovascular age-related macular degeneration (nAMD) patient outcomes and healthcare resource utilization.
Robert P. Finger   +9 more
doaj   +1 more source

The rain feels different under the same umbrella: Experiences with poverty across LGBTQ subgroups

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract Population‐based survey data have demonstrated that LGBTQ communities report varying rates of economic insecurity, yet very little research directly assesses how pathways into and experiences with poverty look different among subgroups at the intersections of sexual orientation and gender identity (SOGI).
Bianca D. M. Wilson, Lillian Nguyen
wiley   +1 more source

New Anti-Telomerase Anti-Cancer Agents

open access: yes, 2008
The unlimited proliferative potential of cancer cells depends on telomere maintenance. Optimal telomerase activity requires in chromosomal DNA an unfolded single-stranded telomeric overhang.
PETRACCONE, LUIGI
core  

Using photovoice to understand community perceptions of firearm risks and protective factors among Asian Americans

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This study used photovoice methodology to explore Asian Americans' perspectives on the root causes and protective factors of firearm violence in their communities. Photovoice provided a participatory platform for community members to document lived experiences and identify priorities for change.
Tsu‐Yin Wu   +4 more
wiley   +1 more source

Freedom dreaming of migrant justice: Critical reflections on counterspaces and institutional violence in the university

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract US universities are built on stolen land and sustained through hierarchies of power that produce what migrant justice scholars name as b/order regimes. As institutions that claim to be sites of learning and inclusion, universities are fraught with contradictions as simultaneously sites of dispossession, exclusion, and control.
Sara L. Buckingham   +1 more
wiley   +1 more source

Occupational Conditions and Well‐Being Among Informal Waste Pickers in Hong Kong: A Comparative Study of 2018 and 2023

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Informal waste pickers play a crucial role in urban recycling systems but often face precarious employment and systematic marginalization. This study examines the evolving demographic, occupational, and health trends of informal waste pickers in Hong Kong between 2018 and 2023.
Siu‐Ming Chan   +6 more
wiley   +1 more source

Evaluation of Anxiolytic Effect of Pantoprazole on Swiss Albino Mice – An Experimental Study

open access: yesInternational Journal of Medical Students
Background: Anxiety disorders, affecting over 7% of the global population, are among the most common psychiatric disorders significantly impairing daily life, productivity, and social functioning.
Farheen Kooliyattayil   +2 more
doaj   +1 more source

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