Results 71 to 80 of about 163,561 (303)

New Anti-Telomerase Anti-Cancer Agents

, 2008
The unlimited proliferative potential of cancer cells depends on telomere maintenance. Optimal telomerase activity requires in chromosomal DNA an unfolded single-stranded telomeric overhang.
PETRACCONE, LUIGI
core  

Exploration of Piperidinols as Potential Antitubercular Agents [PDF]

, 2014
Novel drugs to treat tuberculosis are required and the identification of potential targets is important. Piperidinols have been identified as potential antimycobacterial agents (MIC < 5 μg/mL), which also inhibit mycobacterial arylamine N ...
Elizabeth Fullam, Morris, Garrett M, Edith Sim, Morris, Garrett, Angela J. Russell, Paul Finn, Fullam, Elizabeth, Finn, Paul, Russell, Angela J, Sanjib Bhakta, Garrett M. Morris, Angela Russell, Paul W. Finn, Finn, Paul W, Bhakta, Sanjib, Morris, Garrett M., Areej Abuhammad, Sim, Edith, Abuhammad, Areej, RUSSELL, Angela J., Russell, Angela, Finn, Paul W., Garrett Morris   +22 more
core   +1 more source

An update on the pharmacological treatment of anxiety and related disorders

South African Family Practice, 2016
The anxiety disorders, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD) are common and debilitating, often coexist with medical and psychiatric conditions, and usually require long-term treatment.
K. Outhoff
doaj   +1 more source

Anti-vascular endothelial growth factor in neovascular age-related macular degeneration – a systematic review of the impact of anti-VEGF on patient outcomes and healthcare systems

BMC Ophthalmology, 2020
Background Systematically review the evidence describing the impact of anti–vascular endothelial growth factor (anti-VEGF) therapy on neovascular age-related macular degeneration (nAMD) patient outcomes and healthcare resource utilization.
Robert P. Finger, Vincent Daien, Bora M. Eldem, James S. Talks, Jean-Francois Korobelnik, Paul Mitchell, Taiji Sakamoto, Tien Yin Wong, Krystallia Pantiri, Joao Carrasco   +9 more
doaj   +1 more source

Health‐Related Quality of Life, Everyday Executive Functioning, and Eating Behavior in Adults With Bardet–Biedl Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Bardet–Biedl syndrome (BBS) is a rare genetic condition with a broad phenotypic spectrum. Knowledge about quality of life, executive functioning, and eating behavior in adults with BBS remains limited. This study aimed to assess health‐related quality of life (HRQoL), everyday executive functioning, and eating behavior in adults with BBS and ...
Cecilie Fremstad Rustad, Charlotte von der Lippe, Hilde Nordgarden, Jeanette Ullmann Miller, Mina Susanne Weedon‐Fekjær, Ragnheidur Bragadottir, Solrun Sigurdardottir   +6 more
wiley   +1 more source

Comparison of Y-90 and Ho-166 dosimetry using liver phantom: A Monte Carlo Study7

, 2022
Background: It is estimated that more than 1 million people are diagnosed with liver malignancy each year and one of the treatments is radioembolization with Y-90 and Ho-166.
Kökkülünk, Handan Tanyıldızı, Yıldırım, Ayşe Karadeniz   +1 more
core   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Anti-Cancer Agents in Medicinal Chemistry

, 2013
Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.
CAPRANICO, GIOVANNI
core  

Inter-cultural differences in response to a computer-based anti-bullying intervention [PDF]

, 2010
Background and purpose: Many holistic anti-bullying interventions have been attempted, with mixed success, while little work has been done to promote a 'self-help' approach to victimisation.
Schneider, W., Dautenhahn, K., Hall, L., Enz, S., Paiva, A., Watson, Scott, Watson, S., Wolke, D., Aylett, Ruth, Vannini, Natalie, Watson, Scott E. J., Andre, E., Vannini, N., Woods, Sarah, Paiva, Ana, André, Elisabeth, Prof. Dr., Schneider, Wolfgang, Enz, Sibylle, Woods, S., Dautenhahn, Kerstin, André, Elizabeth, Hall, Lynne, Wolke, Dieter, Sapouna, Maria, Sapouna, M., André, Elisabeth   +25 more
core   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source