Results 51 to 60 of about 70,901 (256)

The relationship between pain intensity and anxiety, injection speed, and intraocular pressure changes during intravitreal anti-vascular endothelial growth factor injection: the observational pilot study

open access: yesBMC Ophthalmology
Purpose To evaluate the relationship between the pain severity and the injection speed, anxiety, and intraocular pressure changes during the intravitreal injection (IVI) of anti-vascular endothelial growth factor (anti-VEGF) agents.
Ali Kurt, Emin Utku Altındal
doaj   +1 more source

Effect of Parecoxib and transversus abdominis plane block on postoperative anxiety and cognition: A randomized controlled-trial

open access: yesJournal of the Pakistan Medical Association
Objective: To investigate the impact of parecoxib and transversus abdominis plane block on postoperative anxiety and early cognitive function in patients undergoing laparoscopic intestinal surgery.
Fuzhen Zhang   +5 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury

open access: yesAdvanced Science, EarlyView.
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu   +12 more
wiley   +1 more source

Antimicrobial and anti-inflammatory activities of endophytic fungi Talaromyces wortmannii extracts against acne-inducing bacteria. [PDF]

open access: yesPLoS ONE, 2014
Acne vulgaris is the most common skin disease, causing significant psychosocial problems such as anxiety and depression similar to a chronic illness for those afflicted. Currently, obtainable agents for acne treatment have limited use.
Alexander Pretsch   +13 more
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

open access: yesAdvanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang   +17 more
wiley   +1 more source

Evaluation of anxiety-like behaviors following ethanol withdrawal in mice: effects of cannabidiol

open access: yesActa Scientiarum. Health Sciences, 2020
The abrupt interruption of ethanol consumption increases anxiety-like behaviors in rodents and may reflect different aspects of ethanol dependence in humans.
Letícia Pin Coltri   +3 more
doaj   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

open access: yesAdvanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang   +8 more
wiley   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

open access: yesAdvanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen   +11 more
wiley   +1 more source

Fatores associados ao uso de medicamentos ansiolíticos entre bombeiros militares

open access: yesRevista Brasileira de Epidemiologia, 2019
RESUMO: Introdução: O uso de ansiolíticos é uma opção no tratamento de sintomas psíquicos. Contudo, ainda que o uso seja controlado há riscos de dependência, intoxicação e alterações cognitivas.
Danielle Sandra da Silva de Azevedo   +2 more
doaj   +1 more source

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