Results 171 to 180 of about 355,535 (359)

The apicobasal dispersion of ventricular repolarization in humans is associated with age and affects arrhythmia vulnerability

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We investigated the age‐ and sex‐related differences in the apicobasal repolarization gradient (ABRG) and evaluated their possible role inventricular arrhythmia vulnerability. Electrocardiographic imaging (ECGI) was performed in healthy subjects during sinus rhythm, and the average recovery time (RT) and activation–recovery ...
Vladimír Sobota   +9 more
wiley   +1 more source

Role of implantable loop recorders in optimizing care for patients during and after left ventricular assist device support: a single centre experience. [PDF]

open access: yesBMC Cardiovasc Disord
Emam AY   +7 more
europepmc   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach   +8 more
wiley   +1 more source

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero   +7 more
wiley   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve   +11 more
wiley   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil   +11 more
wiley   +1 more source

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera   +6 more
wiley   +1 more source

Catheter ablation vs. anti-arrhythmic drug therapy for ventricular tachycardia in ischaemic heart disease: a meta-analysis of randomized controlled trials. [PDF]

open access: yesEuropace
Santoro F   +10 more
europepmc   +1 more source

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