Results 21 to 30 of about 118,647 (313)

Have the Findings from Clinical Risk Prediction and Trials Any Key Messages for Safety Pharmacology?

Frontiers in Physiology, 2017
Anti-arrhythmic drugs are a mainstay in the management of symptoms related to arrhythmias, and are adjuncts in prevention and treatment of life-threatening ventricular arrhythmias.
Jem D. Lane, Jem D. Lane, Andrew Tinker
doaj   +1 more source

Evaluation of the Effectiveness and Use of Anti-Methicillin-Resistant Staphylococcus aureus Agents for Aspiration Pneumonia in Older Patients Using a Nationwide Japanese Administrative Database [PDF]

, 2023
Studies indicated potential harm from empirical broad-spectrum therapy. A recent study of hospitalizations for community-acquired pneumonia suggested that empirical anti-methicillin-resistant Staphylococcus aureus (MRSA) therapy was associated with an ...
Kei Tokutsu, Fujino, Yoshihisa, Yura, Hirokazu, Iwanaga, Naoki, Yuya Ito, Naoki Iwanaga, Daisuke Okuno, Shinya Matsuda, Takashi Kido, Takeda, Kazuaki, Koichi Izumikawa, Yanagihara, Katsunori, Takatomo Tokito, Kazuhiro Yatera, Matsuda, Shinya, Ishimoto, Hiroshi, Katsunori Yanagihara, Sakamoto, Noriho, Fushimi, Kiyohide, Ito, Yuya, Satoru Koga, Tokito, Takatomo, Takahiro Takazono, Hirokazu Yura, Hiroshi Ishimoto, Koga, Satoru, Noriho Sakamoto, Yoshihisa Fujino, Hiroshi Mukae, Muramatsu, Keiji, Kazuaki Takeda, Yatera, Kazuhiro, Okuno, Daisuke, Kido, Takashi, Tokutsu, Kei, Takazono, Takahiro, Keiji Muramatsu, Mukae, Hiroshi, Izumikawa, Koichi, Kiyohide Fushimi   +39 more
core   +1 more source

Case Report: Nadolol–mexiletine combination therapy for refractory neonatal long QT syndrome: a case series beyond sodium channelopathies

Frontiers in Pediatrics
Neonatal long QT syndrome (LQTS) is associated with substantial mortality and poses significant therapeutic challenges, particularly in cases refractory to beta-blocker monotherapy.
Jihye You, Jihye You, Hyun Ho Kim
doaj   +1 more source

Cardioprotective effects of Ferulic acid against various drugs and toxic agents

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background Homeostatic regulation of cardiomyocytes is indispensable in maintaining the normal physiological activity of cardiac tissue. Cardiotoxicity induced by drugs may lead to cardiac abnormalities such as arrhythmia, myocardial infarction and ...
Anandakumar Pandi, Mahto Hemanti Raghu, Naveenkumar Chandrashekar, Vanitha Manickam Kalappan   +3 more
doaj   +1 more source

Identification of phytoconstituents of Tragia involucrata leaf extracts and evaluate their correlation with anti-inflammatory & antioxidant properties.

, 2021
AimsThe present investigation was aimed at exploring the phytoconstituents using Gas Chromatography Mass Spectroscopy and to evaluate antioxidant and anti-inflammatory properties of the leaf extracts.Materials and methodsThe extracts were obtained ...
Dua, K, Chellappan, DK, Velu, V, Radhakrishnan, V, Malipeddi, H, Kumar, N, Mehta, M, Fuloria, S, Gupta, G, Banerjee, S   +9 more
core   +1 more source

Role of Heat Shock Proteins in Atrial Fibrillation: From Molecular Mechanisms to Diagnostic and Therapeutic Opportunities

Cells, 2022
Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell stress response, of which examples are HSP70, HSP60, HSP90, and small HSPs (HSPB).
Daiqi Liu, Xuyao Han, Zhiwei Zhang, Gary Tse, Qingmiao Shao, Tong Liu   +5 more
doaj   +1 more source

Anti-influenza agents from Traditional Chinese Medicine

, 2010
After new human transmissible H1N1 (swine flu) viruses were reported in Mexico and the United States in April 2009, the World Health Organization (WHO) announced the emergence of a novel influenza A virus.
Jiaju Zhou, Zirong Yang, Zhou, Jiaju, Pei-Gen Xiao, Qiong Gu, Wang, Yi-Fei, Wang, YF, Jun Xu, Ge, Hu, Hua Su, Xu, Jun, Gu, Qiong, Yang, Zirong, Hai-Bo Liu, Su, Hua, Liu, Hai-Bo, Xiao, Pei-Gen, Liu, Yanhuai, Hu Ge, Yanhuai Liu, Yi-Fei Wang   +20 more
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

A preliminary assessment of the effects of ATI-2042 in subjects with paroxysmal atrial fibrillation using implanted pacemaker methodology

, 2009
Aims ATI-2042 (budiodarone) is a chemical analogue of amiodarone with a half life of 7 h. It is electrophysiologically similar to amiodarone, but may not have metabolic and interaction side effects.
Camm, AJ, Arya, A, Milner, P, Silberbauer, J, Sulke, N, Teichman, SL   +5 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source