Results 21 to 30 of about 46,906 (308)

Cardiac TdP risk stratification modelling of anti-infective compounds including chloroquine and hydroxychloroquine

open access: yesRoyal Society Open Science, 2021
Hydroxychloroquine (HCQ), the hydroxyl derivative of chloroquine (CQ), is widely used in the treatment of rheumatological conditions (systemic lupus erythematosus, rheumatoid arthritis) and is being studied for the treatment and prevention of COVID-19 ...
Dominic G. Whittaker   +7 more
doaj   +1 more source

Managing atrial fibrillation in the global community: The European perspective. [PDF]

open access: yes, 2013
Atrial fibrillation is a common, global problem, with great personal, economic and social burdens. As populations age it increases in prevalence and becomes another condition that requires careful chronic management to ensure its effects are minimised ...
Camm, AJ   +3 more
core   +1 more source

Successful rescue of fulminant myocarditis with mechanical circulatory support and immunosuppression therapy: A case report

open access: yesFrontiers in Cardiovascular Medicine, 2023
Myocarditis is challenging to diagnose because of its various clinical manifestations. Fulminant myocarditis (FM) is a severe type of myocarditis characterized by heart failure, malignant arrhythmia, cardiogenic shock, and cardiac arrest.
Chi Zhou
doaj   +1 more source

Extrahepatic complications of liver transplantation. [PDF]

open access: yes, 1985
The massive surgical assault associated with hepatic transplantation makes a high frequency of complications almost inevitable. In this review of 225 patient records, selected at random from cases of liver transplantation in Pittsburgh over a 2 1/2 year ...
Shaw, BW, Starzl, TE, Wood, RP
core   +1 more source

Have the Findings from Clinical Risk Prediction and Trials Any Key Messages for Safety Pharmacology?

open access: yesFrontiers in Physiology, 2017
Anti-arrhythmic drugs are a mainstay in the management of symptoms related to arrhythmias, and are adjuncts in prevention and treatment of life-threatening ventricular arrhythmias.
Jem D. Lane, Jem D. Lane, Andrew Tinker
doaj   +1 more source

Cardiovascular Abnormalities in Juvenile Dermatomyositis: A Scoping Review for the Clinical Rheumatologists

open access: yesFrontiers in Medicine, 2022
Juvenile dermatomyositis (JDM) is a common form of inflammatory myositis in children. Vasculopathy and endothelial dysfunction play significant roles in the pathogenesis of JDM.
Sanjib Mondal   +2 more
doaj   +1 more source

Regulation of gap junction function; the role of nitric oxide. [PDF]

open access: yes, 2013
Myocardial ischemia resulting from sudden occlusion of a coronary artery is one of the major causes in the appearance of severe, often life-threatening ventricular arrhythmias.
Gönczi, Márton   +3 more
core   +2 more sources

Cardioprotective effects of Ferulic acid against various drugs and toxic agents

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2022
Background Homeostatic regulation of cardiomyocytes is indispensable in maintaining the normal physiological activity of cardiac tissue. Cardiotoxicity induced by drugs may lead to cardiac abnormalities such as arrhythmia, myocardial infarction and ...
Anandakumar Pandi   +3 more
doaj   +1 more source

Role of Heat Shock Proteins in Atrial Fibrillation: From Molecular Mechanisms to Diagnostic and Therapeutic Opportunities

open access: yesCells, 2022
Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell stress response, of which examples are HSP70, HSP60, HSP90, and small HSPs (HSPB).
Daiqi Liu   +5 more
doaj   +1 more source

Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs). [PDF]

open access: yes, 2001
Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across membranes and are key to the normal function of nerves muscles. They arise from the assembly of four pore-forming proteins called alpha-subunits.
Abbott, GW, Goldstein, SA
core  

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