Results 131 to 140 of about 59,985 (224)

Terpene Hydroperoxides as Lipid Peroxidation Inducers: Biomimetic and HaCaT Cell Studies in Allergic Contact Dermatitis

Contact Dermatitis, EarlyView.
Fragrance terpene hydroperoxides from limonene, linalool, and geraniol induced the formation of lipid peroxidation products when incubated with PLPC liposomes or in vitro with HaCaT keratinocytes. Lipid peroxidation products included aldehydes, ketones, and hydroperoxides.
Aaron I. Moore, Ana S. P. Moreira, Tiago Conde, Tânia Melo, Pedro Domingues, Niamh M. O'Boyle, M. Rosário Domingues   +6 more
wiley   +1 more source

Airway Basal Stem Cells Inflammatory Alterations in COVID‐19 and Mitigation by Mesenchymal Stem Cells

Cell Proliferation, EarlyView.
Airway basal stem cells derived from COVID‐19 patients demonstrated pronounced goblet cell hyperplasia, inflammatory responses and tendencies toward fibrosis. Co‐culture with mesenchymal stem cells (MSCs) notably reduced these pathological changes, likely due to MSCs' regulatory effects on the interferon signalling pathway.
Sheng Du, Jing Jin, Chunli Tang, Zhuquan Su, Lulin Wang, Xinyuan Chen, Mengni Zhang, Yiping Zhu, Jiaojiao Wang, Chunrong Ju, Xinyu Song, Shiyue Li   +11 more
wiley   +1 more source

The gut microbiota modulates airway inflammation in allergic asthma through the gut-lung axis related immune modulation: A review. [PDF]

Biomol Biomed
Zhang M, Qin Z, Huang C, Liang B, Zhang X, Sun W.   +5 more
europepmc   +1 more source

Editorial: Methods in respiratory pharmacology 2023. [PDF]

Front Pharmacol
Milad N, Cabrini G, Cordina M.
europepmc   +1 more source

Nitric Oxide Donor Metallodrug: Single-Inhaler Proposal for Rescue in Acute Allergic Asthma Crises. [PDF]

Biology (Basel)
Costa PPC, Waller SB, Ramos HH, Lopes Neto BE, Ribeiro WLC.   +4 more
europepmc   +1 more source

An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation

The FEBS Journal, EarlyView.
Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti, Silvio Aprile, David Cabañero, Fabio Travagin, Laura Butron, Gregorio Fernández‐Ballester, Gian Cesare Tron, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel, Ubaldina Galli   +9 more
wiley   +1 more source

Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer's disease by administration through an intranasal route. [PDF]

Commun Biol
Groo AC, Curel T, Malzert-Fréon A, Séguy L, Bento O, Corvaisier S, Culerier T, Legrand R, Callizot N, Henriques A, Culley G, Claeysen S, Rochais C, Dallemagne P.   +13 more
europepmc   +1 more source

Pneumocystis jirovecii pneumonia–Immune reconstitution inflammatory syndrome: A review of published cases

HIV Medicine, EarlyView.
Abstract Background Immune reconstitution inflammatory syndrome (IRIS) can occur in patients with HIV after commencing antiretroviral therapy. Tuberculosis–IRIS is the most common, and Pneumocystis jirovecii pneumonia (PJP)–IRIS accounts for only 2.7%–4% of IRIS cases.
Natasha Marcella Vaselli, Kris Salaveria, James Winearls, Katherine Garnham   +3 more
wiley   +1 more source

Evaluation of bronchial hyperresponsiveness in asthmatic paediatric patients using mannitol challenge test - Impacts of body mass index. [PDF]

Ann Med
Leung SSY, Tsang HSL, Chan J, Kui OYH, Zeng P, Cheung YT, Cheng JW, Chan KCC, Yu M, Tang P, Brannan JD, Lam JKW, Chan HK, Li AM.   +13 more
europepmc   +1 more source

Mining bioactive components in agricultural crop and food production residue for sustainable solutions: In silico screening for skin anti‐ageing properties

International Journal of Cosmetic Science, EarlyView.
A workflow for identifying sustainable anti‐ageing solutions from agricultural crop and food production residues (ACFPR). A combination of in silico techniques, like database interrogations, target predictions, molecular docking, and ADME predictions can pave the way for the development of innovative, eco‐friendly anti‐ageing cosmetics.
Senka Vidović, Milan Ilić, Jelena Nakomčić, Nataša Nastić, Jelena Kvrgić, Xuanpeng Song, Dimitar Jakimov, Aleksandra Jovanović Galović, Nataša Lješković Jovanović, Mire Zloh   +9 more
wiley   +1 more source