Results 131 to 140 of about 32,319 (328)
Toxic Homes: Exposure to indoor toxins in Bushwick [PDF]
, 2009 In order to learn how to best address the extensive problem of indoor toxins in people's homes in Bushwick, in the Fall of 2009, Make the Road NY conducted 120 surveys and interviews in the community and compiled this report.
core
Clinical Pharmacology &Therapeutics, EarlyView.Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh +9 more
wiley +1 more source
Extracellular Traps: A Novel Therapeutic Target for Severe Asthma
Journal of Asthma and Allergy, 2022 Youngwoo Choi,1 Quoc Quang Luu,1,2 Hae-Sim Park1,2 1Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea; 2Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, KoreaCorrespondence: Hae ...
Choi Y, Luu QQ, Park HS
doaj
Off-label prescribing for allergic diseases in children
World Allergy Organization Journal, 2014 The majority of drugs prescribed have not been tested in children and safety and efficacy of children’s medicines are frequently supported by low quality of evidence.
Diana Silva +2 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin +6 more
wiley +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Clock gene dysregulation in epilepsy: A systematic review
Epilepsia Open, EarlyView.Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos +3 more
wiley +1 more source
Health Benefits of Polysaccharides in Red Algae: A Comprehensive Review
Food Frontiers, EarlyView.Graphical abstract showing the health benefits of red algal polysaccharides. ABSTRACT Humans have long consumed red algae (especially by the Asian community), and their polysaccharide extracts (carrageenan, agar) are extensively used in the food industry as gel thickeners.
Sammueal Jun Kai Ong +10 more
wiley +1 more source
SYNTHESIS OF SOME NOVEL 1,3,6-TRISUBSTITUTED-1HTHIAZOLO[3,2-f]PURINE-2,4-DIONES AND XANTHINE SCHIFF BASES AS POTENIAL ANTI-ASTHMATIC AND ANTIINFLAMMATORY AGENTS [PDF]
, 2015 Alaa M. Hayallah +2 more
openalex +1 more source