Results 171 to 180 of about 32,098 (325)

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

Correction: A current review on animal models of anti-asthmatic drugs screening. [PDF]

Front Pharmacol
Singh S, Kularia S, Shukla S, Singh M, Kumar M, Sharma AK.   +5 more
europepmc   +1 more source

Clinical guidelines highlight for the hospitalist: Management of cyclic vomiting syndrome in children

Journal of Hospital Medicine, EarlyView.
Yamileth N. Hernandez, Hannah M. Gardner
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Key role of thymic stromal lymphopoietin as a molecular target for biologic treatment of severe asthma. [PDF]

Front Allergy
Pelaia C, Melhorn J, Paoletti G, Poto R, Maglio A, Crimi C, Vatrella A, Canonica GW, Pelaia G.   +8 more
europepmc   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Inhaled anti-asthmatic therapy and tooth wear in children and adolescents: a case-control study. [PDF]

Sci Rep
Świątkowska-Bury M, Zawadzka-Krajewska A, Kulus M, Piekoszewska-Ziętek P, Turska-Szybka A, Olczak-Kowalczyk D.   +5 more
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

GPR43 in eosinophils suppresses the emergence of pathogenic Siglec-F^hi neutrophils in allergic airway inflammation in mice. [PDF]

Nat Commun
Yu J, Kim S, Song HS, Kim J, Shin W, Park JE, Kimura I, Kim HY, Kim YM.   +8 more
europepmc   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source