Results 171 to 180 of about 30,075 (311)

Near-fatal asthma responsive to mepolizumab after failure of omalizumab and bronchial thermoplasty

Therapeutics and Clinical Risk Management, 2017
Francesco Menzella,1 Carla Galeone,1 Mirco Lusuardi,2 Anna Simonazzi,1 Claudia Castagnetti,1 Patrizia Ruggiero,1 Nicola Facciolongo1 1Department of Medical Specialties, Pneumology Unit, Arcispedale Santa Maria Nuova – IRCCS, Azienda USL di Reggio ...
Menzella F, Galeone C, Lusuardi M, Simonazzi A, Castagnetti C, Ruggiero P, Facciolongo N   +6 more
doaj  

Basophil Activation Test: Bridging Allergy and Oncology for Diagnostic, Therapeutic and Prognostic Applications in AllergoOncology: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT The basophil activation test (BAT) is gaining increasing relevance as an ex vivo functional assay in allergy to evaluate IgE‐mediated hypersensitivity reactions to food allergens, venoms, and drugs and to monitor tolerance induction. Establishing universal standard operating protocols has been difficult, due to several challenges including ...
Mariona Pascal, Jitesh Chauhan, Edward Knol, Rodolfo Bianchini, Mariana Castells, Leticia De las Vecillas, Karin Hartmann, Elena Izquierdo, Uta Jappe, Teodorikez‐Wilfox Jimenez‐Rodriguez, Francesca Levi‐Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F. Santos, Erika Jensen‐Jarolim, Christoph Bergmann, Sophia N. Karagiannis, Heather J. Bax   +18 more
wiley   +1 more source

Biologic Therapy in Severe Asthma: A Phenotype-Driven and Targeted Approach. [PDF]

J Clin Med
D'Amato M, Pastore D, Lupia C, Candia C, Bruni A, Garofalo E, Longhini F, Maglio A, Petrone A, Vatrella A, Pelaia G, Pelaia C.   +11 more
europepmc   +1 more source

Effect of the Multi‐Strain Probiotic SYN‐53 in the Management of Allergic Rhinoconjunctivitis

Allergy, EarlyView.
Allergic rhinoconjunctivitis has previously been linked to gut dysbiosis. A double‐blind, placebo‐controlled, randomized clinical trial with the multi‐strain probiotic food supplement SYN‐53 was conducted. Eighty‐four subjects affected by allergic rhinoconjunctivitis were exposed to grass pollen in an allergen exposure chamber to assess safety and ...
Karl‐Christian Bergmann, Torsten Zuberbier   +1 more
wiley   +1 more source

Benzo[a]pyrene aggravated ovalbumin‑induced epithelial tight junction disruption via ROS driven‑NLRP3/Caspase‑1 signaling pathway in asthmatic mice. [PDF]

Int J Mol Med
Xu Y, Feng Y, Wang L, Xu X, Xu L, Wang B.   +5 more
europepmc   +1 more source

Langerhans Cell Modulation in Atopic Dermatitis Is TLR2/SOCS1‐Dependent and JAK Inhibitor‐Sensitive

Allergy, EarlyView.
Constitutive exposure to TLR2 ligands can modify Langerhans cell (LC) activation capacity and outcome, being similar to LC in atopic dermatitis skin. While maturation marker and migration are impaired, the cytokine profile switches and favors atopic dermatitis‐related IL‐1β and IL‐18.
Yuxuan Deng, Nicole Leib, Sylvia Schnautz, Said Benfadal, Johannes Oldenburg, Thomas Bieber, Nadine Herrmann   +6 more
wiley   +1 more source

Naturally derived bioactive compounds as regulators of oxidative stress and inflammation in asthma. [PDF]

Chin Med
Lee J, Choi HK, Shin HS, Kim GD.
europepmc   +1 more source

Predisposing Factors for Erosive Tooth Wear in Permanent Teeth Among Asthmatic Children and Adolescents. [PDF]

Clin Exp Dent Res
Samec TU, Jan J.
europepmc   +1 more source

Epithelial Lining Fluid Cystatin SN is a Noninvasive Biomarker for Predicting Type 2 Chronic Rhinosinusitis

Allergy, EarlyView.
Cystatin SN is highly expressed in the epithelial lining fluid (ELF) of patients with type 2 (T2) chronic rhinosinusitis (CRS). ELF cystatin SN expression correlates with nasal T2/eosinophilic inflammation and impaired olfactory function. ELF cystatin SN is a non‐invasive biomarker for predicting T2 CRS with superior accuracy.
Seojin Moon, Sungmin Moon, Sol Lee, Gyeongyeob Kim, Min‐Seok Koo, Hyung‐Ju Cho, Chang‐Hoon Kim, Min‐Seok Rha   +7 more
wiley   +1 more source

Molecular profiling of exhaled breath condensate in respiratory diseases. [PDF]

Ann Med
Malerba M, Purghè B, Ragnoli B, Manfredi M, Baldanzi G.   +4 more
europepmc   +1 more source