Results 171 to 180 of about 32,319 (328)

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Correction: A current review on animal models of anti-asthmatic drugs screening. [PDF]

Front Pharmacol
Singh S, Kularia S, Shukla S, Singh M, Kumar M, Sharma AK.   +5 more
europepmc   +1 more source

The anti-asthmatic drug MK571 as a potential therapeutic agent for Uveal Melanoma

, 2020
Paulina García de Alba Graue, Alicia A. Goyeneche, Mohamed Abdouh, Tadhg Ferrier, Ana Beatriz Toledo Dias, Alexander Laskaris, Jacqueline Coblentz, Miguel N. Burnier   +7 more
openalex   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

Dictamnine Exhibits Anti-Asthmatic Effects by Modulating TGF-β/Smad2/3 Signaling in a Murine Asthma Model and Human Bronchial Epithelial Cells. [PDF]

Int J Mol Sci
Jung MA, Kim BY, Lee JY, Ji KY, Lee MH, Jung DH, Cai M, Kim T.   +7 more
europepmc   +1 more source

Progress in Surface‐Enhanced Raman Scattering‐Based Volatile Organic Compounds Detection: Materials, Application, and Prospects

Rare Metals, EarlyView.
ABSTRACT The detection of volatile organic compounds (VOCs) holds significant implications in environmental monitoring and disease diagnosis. Traditional gas detection technologies are constrained by complex operation and high cost, thereby failing to satisfy real‐time detection demands.
Yuening Wang, Lin Qiu, Jian Yu, Wen Ma, Xiaoyu Song, Mingjian Zhang, Yujiao Xie, Aochi Liu, Li Sun, Xiangyu Meng, Jie Lin, Xiaotian Wang   +11 more
wiley   +1 more source

Key role of thymic stromal lymphopoietin as a molecular target for biologic treatment of severe asthma. [PDF]

Front Allergy
Pelaia C, Melhorn J, Paoletti G, Poto R, Maglio A, Crimi C, Vatrella A, Canonica GW, Pelaia G.   +8 more
europepmc   +1 more source

Prognostic Value of a Cardiopulmonary Exercise Testing‐Derived Summed Score in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease‐Associated Interstitial Lung Disease: A Prospective Cohort Study

Respirology, EarlyView.
A cardiopulmonary exercise testing‐derived summed score effectively predicted mortality or lung transplantation risk in newly diagnosed interstitial lung disease. Higher summed scores (2–5) were associated with markedly lower event‐free survival rates.
Yu‐Lin Tsai, Kai‐Ming Chang, Chung‐Shih Chin, Chiann‐Yi Hsu, Yi‐Hsuan Yu, Yuan‐Yang Cheng, Pin‐Kuei Fu   +6 more
wiley   +1 more source

Inhaled anti-asthmatic therapy and tooth wear in children and adolescents: a case-control study. [PDF]

Sci Rep
Świątkowska-Bury M, Zawadzka-Krajewska A, Kulus M, Piekoszewska-Ziętek P, Turska-Szybka A, Olczak-Kowalczyk D.   +5 more
europepmc   +1 more source