Results 181 to 190 of about 59,985 (224)

The Effects of Turmeric and Mangosteen Pericarp Ethanol Extract on Eosinophil Count, TNF-α and TGF-β1 Gene Expression in Asthmatic Rat Model. [PDF]

J Exp Pharmacol
Elizabeth E, Rohmawaty E, Bashari MH.
europepmc   +1 more source

Ibudilast Protects Retinal Bipolar Cells From Excitotoxic Retinal Damage and Activates the mTOR Pathway

Glia, Volume 73, Issue 5, Page 905-927, May 2025.
Main Points Ibudilast, a MIF and PDE inhibitor, preserves the form and function of the retina, especially bipolar cells, during excitotoxic damage. Ibudilast upregulates multiple signaling pathways, including mTOR, in damaged Müller glia and bipolar cells.
Sumaya Hamadmad, Tyler Heisler‐Taylor, Sandeep Goswami, Evan Hawthorn, Sameer Chaurasia, Dena Martini, Diana Summitt, Ali Zatari, Rahaf Shalash, Misha Sohail, Elizabeth G. Urbanski, Kayla Bernstein, Julie Racine, Abhay Satoskar, Heithem M. El‐Hodiri, Andy J. Fischer, Colleen M. Cebulla   +16 more
wiley   +1 more source

Challenges With the Intolerance of Biologics in Severe Eosinophilic Asthma: The Risk of Exacerbations Is Time-Dependent With the Rise of Eosinophils. [PDF]

Cureus
Cortes-Telles A, Pou-Aguilar YN, Figueroa-Hurtado E, Vazquez-Lopez S, Ortiz DL.   +4 more
europepmc   +1 more source

Replenish Revenue by Low‐Cost Medicines, an Institution‐Specific Action to Improve Access to High‐Cost Medicines Used for Chronic Illness in Ethiopia: Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background Over one‐quarter of the global population has no access to essential medicines. Improving access to medicines for chronic illness requires multi‐level interventions. Nearly half of the people who need insulin cannot afford it. Aim To describe institution‐specific interventions that can be applied to improve access to high‐cost ...
Mende Mensa Sorato
wiley   +1 more source

Oxidative Stress and Antioxidants in Pediatric Asthma's Evolution and Management. [PDF]

Antioxidants (Basel)
Ioniuc IK, Lupu A, Dragan F, Tarnita I, Alexoae MM, Streanga V, Mitrofan C, Thet AA, Nedelcu AH, Salaru DL, Burlea SL, Mitrofan EC, Lupu VV, Azoicai AN.   +13 more
europepmc   +1 more source

Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
ABSTRACT Dysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and metabolic abnormalities.
Yao Shen, Nairui Fan, Shu‐xia Ma, Xin Cheng, Xuesong Yang, Guang Wang   +5 more
wiley   +1 more source

Inhaled tea polyphenol-loaded nanoparticles coated with platelet membranes largely attenuate asthmatic inflammation. [PDF]

Respir Res
Ouyang S, Lu P, Li J, Jin H, Wu W, Luo R, Wang B, Huang X, Lian X, Huang G.   +9 more
europepmc   +1 more source

Alopecia Areata: Pathogenesis, Diagnosis, and Therapies

MedComm, Volume 6, Issue 5, May 2025.
This review probed into the immune factors in the pathogenesis of AA, focusing on the small molecule drugs and biologics for the treatment of AA, and anticipated the research direction in terms of the pathogenesis and targeted therapy of AA. It aims to emphasize the necessity for further exploration of its immunological pathogenesis and therapeutic ...
Tianyou Ma, Tingrui Zhang, Fengze Miao, Jun Liu, Quangang Zhu, Zhongjian Chen, Zongguang Tai, Zhigao He   +7 more
wiley   +1 more source

Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. [PDF]

Molecules
Es-Sai B, Wahnou H, Benayad S, Rabbaa S, Laaziouez Y, El Kebbaj R, Limami Y, Duval RE.   +7 more
europepmc   +1 more source

Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application

MedComm, Volume 6, Issue 5, May 2025.
Molecular hydrogen, delivered through inhalation, hydrogen‐rich water, or hydrogen solution injection, reduces oxidative stress, regulates immune responses, facilitates cell repair, and alleviates inflammatory bowel disease (IBD) and intestinal injury.
Jiayi Jin, Lijun Yue, Maoru Du, Feng Geng, Xue Gao, Yuming Zhou, Qianqian Lu, Xiaohong Pan   +7 more
wiley   +1 more source