Results 271 to 280 of about 32,098 (325)
Objectives: Inhaled corticosteroids, leukotriene receptor antagonists, and theophylline are recommended for the treatment of mild persistent asthma. The aim of this study was to compare the changes in sputum total cell and eosinophil counts, and eosinophil cationic protein (ECP) levels in serum and sputum following treatment with leukotriene receptor ...
İlknur Başyiğit +5 more
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Experimental study of a potential anti-asthmatic agent: SCH 15280.
A forced oscillations technique for measuring total respiratory system resistance was used to quantitate the bronchomotor activity of Sch 15280: (5[4-(N-methyl)-piperidylidine]5H-[1]-benzopyrano[2,3,b]-pyridine maleate) and to compare its potency to that of standard bronchodilator agents.
L. Diamond +3 more
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Protective Effect of a New Anti‐Asthmatic Agent (Minocromil) in Bronchial Allergen Challenge Tests
Ten patients were included in a double‐blind crossover trial, designed to compare the effects of a new anti‐asthmatic agent Minocromil, an organic decarboxylic acid, and placebo on bronchial allergen challenge. The challenges were performed at weekly intervals.
U. G. Svendsen +3 more
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Ginsenoside Compound K (CK) showed potent activity against IgE for the treatment of asthma. A series of CK analogues were then synthesized by straightforward procedures. The in vivo anti-IgE activity evaluations using the OVA-induced asthmatic mouse model revealed preliminary SARs of the CK analogues, which showed that the sugar type, modifications on ...
Sumei Ren +4 more
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Ovalbumin (OVA)-induced asthma in mouse lungs causes changes in the mRNA and protein levels of aquaporins (AQPs). AQP expression was examined in the presence of various anti-asthmatic agents, including dexamethasone, ambroxol, and terbutaline. The influence of these agents on OVA-induced airway inflammation was also evaluated.
Chunling Dong +7 more
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SummaryBackground Dendritic cells (DCs) play an important role in the immune response and are critically involved in asthma. β2‐agonists could potentially exacerbate type 2 T helper (Th2) cell‐mediated immune response.Objectives To determine the effects of various anti‐asthmatic agents on DCs function both in vitro and in vivo.Methods
Ikuko Machida +8 more
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To characterize the antagonistic action of KC-404, an anti-asthmatic agent, against the tachykinin-mediated bronchoconstriction, we studied the effect of this drug on the contractile responses of rabbit tracheal smooth muscle to neurokinin A (NKA) and substance P (SP) under isometric conditions in vitro.
Jun Tamaoki +4 more
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Patent Evaluation: Tricyclic Antihistamines as Anti-asthmatic Agents
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Asthmatic symptoms are worsened after drinking small amounts of alcoholic beverages in Japanese asthmatic patients. Our previous results showed that the ingestion of pure ethanol caused a fall in FEV1.0 in about half of the Japanese asthmatics we studied.
Toshiaki Watanabe +8 more
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