Results 271 to 280 of about 32,098 (325)

Effects of different anti‐asthmatic agents on induced sputum and eosinophil cationic protein in mild asthmatics

open access: closedRespirology, 2004
Objectives:  Inhaled corticosteroids, leukotriene receptor antagonists, and theophylline are recommended for the treatment of mild persistent asthma. The aim of this study was to compare the changes in sputum total cell and eosinophil counts, and eosinophil cationic protein (ECP) levels in serum and sputum following treatment with leukotriene receptor ...
İlknur Başyiğit   +5 more
openalex   +4 more sources

Experimental study of a potential anti-asthmatic agent: SCH 15280.

open access: closedThe Journal of Pharmacology and Experimental Therapeutics, 1975
A forced oscillations technique for measuring total respiratory system resistance was used to quantitate the bronchomotor activity of Sch 15280: (5[4-(N-methyl)-piperidylidine]5H-[1]-benzopyrano[2,3,b]-pyridine maleate) and to compare its potency to that of standard bronchodilator agents.
L. Diamond   +3 more
openalex   +3 more sources

Protective Effect of a New Anti‐Asthmatic Agent (Minocromil) in Bronchial Allergen Challenge Tests

open access: closedAllergy, 1985
Ten patients were included in a double‐blind crossover trial, designed to compare the effects of a new anti‐asthmatic agent Minocromil, an organic decarboxylic acid, and placebo on bronchial allergen challenge. The challenges were performed at weekly intervals.
U. G. Svendsen   +3 more
openalex   +3 more sources

Synthesis and biological evaluation of Ginsenoside Compound K analogues as a novel class of anti-asthmatic agents

open access: closedBioorganic & Medicinal Chemistry Letters, 2018
Ginsenoside Compound K (CK) showed potent activity against IgE for the treatment of asthma. A series of CK analogues were then synthesized by straightforward procedures. The in vivo anti-IgE activity evaluations using the OVA-induced asthmatic mouse model revealed preliminary SARs of the CK analogues, which showed that the sugar type, modifications on ...
Sumei Ren   +4 more
openalex   +3 more sources

Anti-asthmatic agents alleviate pulmonary edema by upregulating AQP1 and AQP5 expression in the lungs of mice with OVA-induced asthma

open access: closedRespiratory Physiology & Neurobiology, 2011
Ovalbumin (OVA)-induced asthma in mouse lungs causes changes in the mRNA and protein levels of aquaporins (AQPs). AQP expression was examined in the presence of various anti-asthmatic agents, including dexamethasone, ambroxol, and terbutaline. The influence of these agents on OVA-induced airway inflammation was also evaluated.
Chunling Dong   +7 more
openalex   +3 more sources

Effects of various anti‐asthmatic agents on mite allergen‐pulsed murine bone marrow‐derived dendritic cells

open access: closedClinical & Experimental Allergy, 2005
SummaryBackground Dendritic cells (DCs) play an important role in the immune response and are critically involved in asthma. β2‐agonists could potentially exacerbate type 2 T helper (Th2) cell‐mediated immune response.Objectives To determine the effects of various anti‐asthmatic agents on DCs function both in vitro and in vivo.Methods
Ikuko Machida   +8 more
openalex   +3 more sources

Effect of the anti-asthmatic agent KC-404 on the contractile responses of rabbit airway smooth muscle to tachykinins.

open access: closedArerugi = [Allergy], 1990
To characterize the antagonistic action of KC-404, an anti-asthmatic agent, against the tachykinin-mediated bronchoconstriction, we studied the effect of this drug on the contractile responses of rabbit tracheal smooth muscle to neurokinin A (NKA) and substance P (SP) under isometric conditions in vitro.
Jun Tamaoki   +4 more
openalex   +2 more sources

[The inhibitory effects of anti-asthmatic agents on ethanol-induced bronchoconstriction in Japanese asthmatic patients].

open access: closedArerugi = [Allergy], 1992
Asthmatic symptoms are worsened after drinking small amounts of alcoholic beverages in Japanese asthmatic patients. Our previous results showed that the ingestion of pure ethanol caused a fall in FEV1.0 in about half of the Japanese asthmatics we studied.
Toshiaki Watanabe   +8 more
openalex   +2 more sources

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